Evidence map›Paper›PMID 39268086›Full record

ArticleFrontiers in cell and developmental biology2024

Identifying the roles of miR-17 in ciliogenesis and cell cycle.

Ashwaq Alanazi, Ayan K Barui, Ashraf M Mohieldin, Ankan Gupta, Ramani Ramchandran, Surya M Nauli

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Oxidative Stress and its Role in Carcinogenesis.Cell biochemistry and biophysics · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashwaq AlanaziDepartment of Biomedical and Pharmaceutical Sciences, Chapman University, Irvine, CA, United States.
Ayan K BaruiDepartment of Biomedical and Pharmaceutical Sciences, Chapman University, Irvine, CA, United States.
Ashraf M MohieldinDepartment of Pharmaceutical Sciences, California Northstate University, Elk Grove, CA, United States.
Ankan GuptaDepartment of Pediatrics, Division of Neonatology, Medical College of Wisconsin, Milwaukee, WI, United States.
Ramani RamchandranDepartment of Pediatrics, Division of Neonatology, Medical College of Wisconsin, Milwaukee, WI, United States.
Surya M NauliDepartment of Biomedical and Pharmaceutical Sciences, Chapman University, Irvine, CA, United States.

Funding

The roles of neuronal primary cilia in Alzheimer's diseaseR01HL147311 · NHLBI · CHAPMAN UNIVERSITY · PI ALACHKAR, AMAL, NAULI, SURYA · 2020 to 2023
$2.1M
Cilia as a biomarker of CNS vascular healthR33HL154254 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI NAULI, SURYA, PALECEK, SEAN P · 2022 to 2024
$1.9M
The signaling mechanism of primary cilia in aneurysm preventionR56HL131577 · NHLBI · CHAPMAN UNIVERSITY · PI NAULI, SURYA · 2017 to 2017
$345k
NHLBI NIH HHS R01 HL147311NHLBI NIH HHS R33 HL154254NHLBI NIH HHS R56 HL131577
6 · The paper itself

Abstract

Emerging evidence suggests a significant contribution of primary cilia to cell division and proliferation. MicroRNAs, especially miR-17, contribute to cell cycle regulation and proliferation. Recent investigations have highlighted the dysregulated expression of miR-17 in various malignancies, underlining its potential role in cancer. However, the correlation between primary cilia and miR-17 has yet to be fully elucidated. The present study examines the presence of miR-17 in primary cilia. The miR-17 expression is studied in selected ciliary protein knockdown cells. Using

Indexed as

cell migrationcell proliferationGM3SMicroRNAsPGRMC2PKD2primary cilia

Identifiers

PMID39268086
PMCPMC11390542

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.