Evidence map›Paper›PMID 39267754›Full record

ReviewFrontiers in immunology2024

Plasma concentrations of IL-6, MIP-1β, IP-10, and PTX-3 as predictors of the immunological response to antiretroviral treatment in people with HIV.

Marta Mejías-Trueba, Abraham Saborido-Alconchel, Ana Serna-Gallego, María Trujillo-Rodríguez, Esperanza Muñoz-Muela, Silvia Llaves-Flores, Nuria Espinosa, Cristina Roca-Oporto, Marta Herrero, Cesar Sotomayor and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Persistent CD8Frontiers in immunology · 2026
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marta Mejías-TruebaDepartment of Pharmacy, University Hospital Virgen del Rocío, Seville, Spain.
Abraham Saborido-AlconchelClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
Ana Serna-GallegoClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
María Trujillo-RodríguezClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
Esperanza Muñoz-MuelaClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
Silvia Llaves-FloresClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
Nuria EspinosaClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
Cristina Roca-OportoClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
Marta HerreroClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
Cesar SotomayorClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.
Luis F López-CortesClinical Unit of Infectious Diseases, Clinical Microbiology and Parasitology. Institute of Biomedicine of Seville/Virgen del Rocio University Hospital/CSIC/University of Seville, Seville, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite effective antiretroviral therapy (ART), 15-30% of people with HIV experience poor CD4

Indexed as

BiomarkersChemokine CCL4Chemokine CXCL10C-Reactive ProteinHIV InfectionsInterleukin-6Serum Amyloid P-ComponentAdultAnti-HIV AgentsAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveCD4-CD8 RatioFemaleHumansMaleMiddle AgedAnti-HIV AgentsAnti-Retroviral AgentsBiomarkersCCL4 protein, humanChemokine CCL4Chemokine CXCL10C-Reactive ProteinCXCL10 protein, humanIL6 protein, humanInterleukin-6PentraxinsSerum Amyloid P-ComponentHIV infectionIL-6immunologic responseIP-10MIP-1βPTX-3

Identifiers

PMID39267754
PMCPMC11390504

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.