Evidence map›Paper›PMID 39267751›Full record

ArticleFrontiers in immunology2024

Inflammatory response and parasite regulation in acute toxoplasmosis: the role of P2X7 receptor in controlling virulent atypical genotype strain of

Thuany Prado-Rangel, Aline Cristina Abreu Moreira-Souza, Sthefani Rodrigues Batista da Silva, Thais Barboza-Araujo, Archimedes Barbosa Castro-Junior, Isalira Peroba Rezende Ramos, Christina Maeda Takiya, Rossiane Claudia Vommaro, Robson Coutinho-Silva

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thuany Prado-RangelLaboratório de Imunofisiolofia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Aline Cristina Abreu Moreira-SouzaLaboratório de Imunofisiolofia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Sthefani Rodrigues Batista da SilvaLaboratório de Imunofisiolofia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Thais Barboza-AraujoLaboratório de Ultraestrutura Celular Hertha Meyer, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Archimedes Barbosa Castro-JuniorLaboratório de Imunofisiolofia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Isalira Peroba Rezende RamosCentro Nacional de Biologia Estrutural e Bioimagem-CENABIO, Universidade Federal do Rio de Janeiro, UFRJ, Rio de Janeiro, Brazil.
Christina Maeda TakiyaLaboratório de Imunopatologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Rossiane Claudia VommaroLaboratório de Ultraestrutura Celular Hertha Meyer, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Robson Coutinho-SilvaLaboratório de Imunofisiolofia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasmosis is a globally significant disease that poses a severe threat to immunocompromised individuals, especially in Brazil, where a high prevalence of virulent and atypical strains of

Indexed as

GenotypeMice, Inbred C57BLMice, KnockoutReceptors, Purinergic P2X7ToxoplasmaAcute DiseaseAnimalsCytokinesFemaleInflammationLiverMiceNLR Family, Pyrin Domain-Containing 3 ProteinParasite LoadToxoplasmosisToxoplasmosis, AnimalCytokinesNLR Family, Pyrin Domain-Containing 3 ProteinP2rx7 protein, mouseReceptors, Purinergic P2X7Brazilian strainEGS straininflammationparasite controlpurinergic signalingtoxoplasmosis

Identifiers

PMID39267751
PMCPMC11390460

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.