Evidence map›Paper›PMID 39267728›Full record

ArticlePlastic and reconstructive surgery. Global open2024

Fat Necrosis in Single Perforator Deep Inferior Epigastric Artery and Superficial Epigastric Artery Perforator Free Flaps: A Prospective Randomized Study.

Rebecca L R Miller, Christopher M Nguyen, Blair R Peters, Leif Sigurdson, Thomas E J Hayakawa, Rae Spiwak, Kimberly Dalke, Edward W Buchel

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rebecca L R MillerFrom the Section of Plastic Surgery, Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
Christopher M NguyenFrom the Section of Plastic Surgery, Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
Blair R PetersFrom the Section of Plastic Surgery, Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
Leif SigurdsonFrom the Section of Plastic Surgery, Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
Thomas E J HayakawaFrom the Section of Plastic Surgery, Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
Rae SpiwakDepartment of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Kimberly DalkeFrom the Section of Plastic Surgery, Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
Edward W BuchelFrom the Section of Plastic Surgery, Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The deep inferior epigastric perforator (DIEP) flap is the standard of care in autologous breast reconstruction. The superficial inferior epigastric artery perforator flap (SIEA) is an alternative reconstructive option, with the compromise of less donor-site morbidity but variable perfusion to subscarpal fat zones. Fat necrosis is a known complication from marginal perfusion variability. Volumetric analysis of fat necrosis has not been performed between the two reconstructive options, nor has the amount of flap necrosis following radiation. Our objective was to compare rates and volume of fat necrosis between single-perforator DIEP and SIEA flap techniques. Methods: A single-center, blinded, prospective cohort study of patients randomized between SIEA and DIEP breast reconstruction was conducted over 2 years (June 2011-July 2013). Inclusion criteria were women undergoing immediate reconstruction following mastectomy. Randomization protocols were strictly followed. Fat necrosis volumetric analysis was determined by an ultrasound-trained attending surgeon at 12 months postoperatively. Patient demographics and adjuvant/neoadjuvant cancer treatment were analyzed. Statistical analyses included Mann-Whitney U tests, chi square, and/or Fisher exact tests. Results: Fat necrosis was detected in 11 of 46 flaps (23.9%), with a median area of 17.9 cm Conclusion: Single-perforator DIEP and SIEA flaps have comparable rates of fat necrosis. Postoperative radiation did not result in increased prevalence or extent of fat necrosis.

Identifiers

PMID39267728
PMCPMC11392491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.