Evidence map›Paper›PMID 39267674›Full record

ArticleAmerican journal of cancer research2024

Sophocarpine inhibits the progression of glioblastoma via PTEN/PI3K/Akt signaling pathway.

Shuqiao Xing, Zhenrong Xiong, Mengmeng Wang, Yifan Li, Jiali Shi, Yiming Qian, Jia Lei, Jiamei Jia, Weiquan Zeng, Zhihui Huang and 1 more

Abstract read
In one paragraph

Article in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. CCL20 Expression via AKT-ERK1/2-AP1 Pathway inJournal of inflammation research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shuqiao XingSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Zhenrong XiongSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Mengmeng WangSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Yifan LiSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Jiali ShiSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Yiming QianSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Jia LeiSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Jiamei JiaSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Weiquan ZengSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Zhihui HuangSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.
Yuanyuan JiangSchool of Pharmacy, Hangzhou Normal University Hangzhou 311121, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma multiforme (GBM) is the most fatal primary brain tumor which lacks effective treatment drugs. Alkaloids are known as a class of potential anti-tumor agents. Sophocarpine, a tetracyclic quinazoline alkaloid derived from

Indexed as

cell apoptosiscell cycle arrestglioblastomaPTEN/PI3K/AktSophocarpine

Identifiers

PMID39267674
PMCPMC11387860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.