Evidence map›Paper›PMID 39267515›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

[A case report of Crohn's disease in a child with trisomy 8].

Jiao Xing, Juan Xu, Zhi-Feng Liu, Wei-Xia Cheng

Abstract readCase ReportsEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiao XingDepartment of Gastroenterology, Children's Hospital of Nanjing Medical University, Nanjing 210000, China.
Juan Xu
Zhi-Feng LiuDepartment of Gastroenterology, Children's Hospital of Nanjing Medical University, Nanjing 210000, China.
Wei-Xia ChengDepartment of Gastroenterology, Children's Hospital of Nanjing Medical University, Nanjing 210000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The patient is a 12-year-old male who has experienced recurrent perianal abscesses for over 10 years, along with recurrent oral ulcers and deformities in the joints of hands and feet. Gastrointestinal endoscopy and capsule endoscopy revealed multiple ulcers in the digestive tract. Combined with his histopathological examinations, the patient was diagnosed with Crohn's disease. Whole exome sequencing and peripheral blood karyotype analysis indicated a karyotype of 47,XY,+8. The patient was treated with a "step-up" strategy. His clinical symptoms were under control, with significant improvement observed during endoscopic examination. This case suggests that early-onset inflammatory bowel disease may have genetic susceptibility, and when accompanied by other multi-system involvement, the possibility of chromosomal abnormalities, such as trisomy 8, should be considered and given due attention.

Indexed as

Chromosomes, Human, Pair 8Crohn DiseaseTrisomyChildHumansMaleChildCrohn's diseaseEarly-onset inflammatory bowel diseasePerianal abscessTrisomy 8

Identifiers

PMID39267515
PMCPMC11404466

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.