Observational studyPediatric pulmonology2024
Ventilator variables predicting extubation readiness in extremely premature infants with prolonged mechanical ventilation: A retrospective observational study.
Observational study in Pediatric pulmonology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- MetaboSense: An Integrated Quantum Dot-Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In-Line Monitoring of Lung Metabolism During Ex Vivo Perfusion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ventilator variables predicting extubation readiness in extremely premature infants with prolonged mechanical ventilation: A retrospective observational study.Pediatric pulmonology · 2024Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe current generation of neonatal ventilators enables periodic storage of set, measured, and calculated ventilatory parameters.
designRetrospective observational study.
objectivesTo evaluate and identify the ventilatory, demographic, and clinical pre-extubation variables that are significant for estimating extubation readiness.
methodsEligible subjects included premature infants <33 weeks of gestation weaned from mechanical ventilation (MV) lasting >24 h. A total of 16 relevant ventilator variables, each calculated from 288 data points over 24 h, together with eight demographic and three clinical pre-extubation variables, were used to create the generalized linear model (GLM) for a binary outcome and the Cox proportional hazards model for time-to-event analysis. The achievement of a 120-h period without reintubation was defined as a successful extubation attempt (EA) within the binary outcome.
resultsWe evaluated 149 EAs in 81 infants with a median (interquartile range) gestational age of 25
conclusionsVentilator variables reflecting lung mechanical properties and the ability to spontaneously breathe during MV contribute to better prediction of extubation readiness in extremely premature infants with chronic lung disease.
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