Evidence map›Paper›PMID 39267442›Full record

ArticleThe journal of physical chemistry. B2024

Understanding the Effect of Ionic Liquid-Mediated Solvent Engineering on the Kinetics and Thermodynamic Stability of Phenylalanine Ammonia-Lyase.

Pranav Bharadwaj, Avishak Barua, Meena Bisht, Dheeraj Kumar Sarkar, Sagar Biswas, Gregory Franklin, Dibyendu Mondal

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pranav BharadwajInstitute of Plant Genetics (IPG), Polish Academy of Sciences, Poznań 60-479, Poland.
Avishak BaruaInstitute of Plant Genetics (IPG), Polish Academy of Sciences, Poznań 60-479, Poland.
Meena BishtInstitute of Plant Genetics (IPG), Polish Academy of Sciences, Poznań 60-479, Poland.
Dheeraj Kumar SarkarTata Institute of Fundamental Research, Hyderabad 50046, India.
Sagar BiswasInstitute of Plant Genetics (IPG), Polish Academy of Sciences, Poznań 60-479, Poland.
Gregory FranklinInstitute of Plant Genetics (IPG), Polish Academy of Sciences, Poznań 60-479, Poland.ORCID 0000-0002-6745-3528
Dibyendu MondalInstitute of Plant Genetics (IPG), Polish Academy of Sciences, Poznań 60-479, Poland.ORCID 0000-0002-1715-5514

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenylalanine ammonia-lyase (PAL) plays a central role in the phenylpropanoid pathway and in the treatment of phenylketonuria. However, the integration of PAL into sustainable industrial biocatalysis is hampered by its instability under harsh conditions. This study demonstrates that ionic liquid (IL)-assisted solvent (Tris-HCl buffer) engineering enables improvement of the reaction kinetics and thermodynamic stability of

Indexed as

Enzyme StabilityIonic LiquidsPhenylalanine Ammonia-LyaseSolventsThermodynamicsKineticsMolecular Docking SimulationRhodotorulaIonic LiquidsPhenylalanine Ammonia-LyaseSolvents

Identifiers

PMID39267442
PMCPMC11440588

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.