Evidence map›Paper›PMID 39267402›Full record

GuidelineRevista de neurologia2024

[Advances and guidance in the treatment of drug-resistant epilepsy: a review by the Andalusian Epilepsy Society of the new drugs cenobamate, fenfluramine and cannabidiol].

C Arenas-Cabrera, P Cabezudo-García, R Calvo-Medina, B Galeano-Bilbao, P Martínez-Agredano, J Ruiz-Giménez, J J Rodríguez-Uranga, P Quiroga-Subirana

Abstract readReviewPractice GuidelineEnglish Abstract
In one paragraph

Guideline in Revista de neurologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C Arenas-CabreraHospital Virgen del Rocío, Sevilla, España.
P Cabezudo-GarcíaHospital Regional Universitario de Málaga, Málaga, España.
R Calvo-MedinaHospital Regional Universitario Materno-Infantil de Málaga, Málaga, España.
B Galeano-BilbaoHospital Universitario Puerta del Mar, 11009 Cádiz, España.
P Martínez-AgredanoHospital Universitario Reina Sofía, 14004 Córdoba, España.
J Ruiz-GiménezHospital General Universitario Virgen de las Nieves, Granada, España.
J J Rodríguez-UrangaCentro de Neurología Avanzada, Sevilla, España.
P Quiroga-SubiranaComplejo Hospitalario Torrecárdenas, Almería, España.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review, conducted by the Andalusian Epilepsy Society, provides an update on recent advances in the treatment of drug-resistant epilepsy, focusing on three new anti-seizure drugs: cenobamate, fenfluramine and cannabidiol. These emerging drugs offer new therapeutic alternatives for patients with drug-resistant focal epilepsy, Dravet syndrome, and Lennox-Gastaut syndrome. The primary objective of this review is to provide healthcare professionals with an up-to-date overview of the efficacy, safety and potential clinical applications of these treatments, backed by the latest evidence. In addition to reviewing the available clinical evidence, the document addresses essential practical considerations for the implementation of these drugs in routine clinical practice, including aspects such as their dosage, drug interactions, and management of their side-effects. With this review, the Andalusian Epilepsy Society aims to contribute to improving the care for and quality of life of patients with drug-resistant epilepsy and their families.

Indexed as

AnticonvulsantsCannabidiolCarbamatesDrug Resistant EpilepsyFenfluramineChlorophenolsEpilepsies, MyoclonicHumansLennox Gastaut SyndromeTetrazolesAnticonvulsantsCannabidiolCarbamatesCenobamateChlorophenolsFenfluramineTetrazoles

Identifiers

PMID39267402
PMCPMC11469102

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.