Evidence map›Paper›PMID 39267111›Full record

ArticleJournal of translational medicine2024

Prognostic impact of nectin-like molecule-5 (CD155) expression in non-small cell lung cancer.

Xitlally Popa-Navarro, Alejandro Avilés-Salas, Norma Hernández-Pedro, Mario Orozco-Morales, Enrique Caballé-Pérez, Cesar Castillo-Ruiz, José Lucio-Lozada, Pedro Barrios-Bernal, Juan-Manuel Hernandez-Martinez, Oscar Arrieta

Erratum issuedAbstract read
In one paragraph

Article in Journal of translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Xitlally Popa-NavarroPersonalized Medicine Laboratory, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico.
Alejandro Avilés-SalasPathology department, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico.
Norma Hernández-PedroPersonalized Medicine Laboratory, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico. nhernandezp@incan.edu.mx.
Mario Orozco-MoralesPersonalized Medicine Laboratory, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico.
Enrique Caballé-PérezThoracic Oncology Unit, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico.
Cesar Castillo-RuizPersonalized Medicine Laboratory, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico.
José Lucio-LozadaPersonalized Medicine Laboratory, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico.
Pedro Barrios-BernalPersonalized Medicine Laboratory, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico.
Juan-Manuel Hernandez-MartinezCONAHCYT-Instituto Nacional de Cancerología, Mexico City, Mexico.
Oscar ArrietaThoracic Oncology Unit, Instituto Nacional de Cancerología (INCan), Mexico City, 14080, Mexico. ogar@unam.mx.ORCID 0000-0002-1164-3779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCD155 is a transmembrane protein that inhibits antitumor immune response and represents a predictor of worse prognosis in non-small-cell lung cancer (NSCLC). However, it remains unexplored its association with clinical characteristics and genomic status of Latin American patients. This study characterizes the CD155 expression and its clinical implications in this population.

methodsTissue biopsies from 86 patients with locally-advanced or metastatic NSCLC were assessed for CD155 protein expression, ALK rearrangements and EGFR mutations. Cutoff values for high CD155 expression (CD155

resultsthe cutoff score for CD155

conclusionCD155

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsReceptors, VirusAdultAgedAged, 80 and overErbB ReceptorsFemaleHumansMaleMiddle AgedMutationPrognosisROC CurveErbB Receptorspoliovirus receptorReceptors, VirusCD155Immune checkpointsNectin-like molecule 5Non-small-cell lung cancerOncogene driver mutationsPD-L1

Identifiers

PMID39267111
PMCPMC11391680

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.