Evidence map›Paper›PMID 39266938›Full record

Trial reportJournal of cancer survivorship : research and practice2026

Does sexual rehabilitation work for gay and bisexual prostate cancer patients? Acceptability, feasibility, and efficacy results from the Restore-2 randomized controlled trial.

B R Simon Rosser, Nidhi Kohli, Alex J Bates, Kristine M C Talley, Morgan M Wright, Elizabeth J Polter, Christopher W Wheldon, Ryan Haggart, Daniel R Dickstein, Michael W Ross and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03923582 (Training for Health Professionals in Tanzania), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03923582 nacompletednot on this map

Training for Health Professionals in Tanzania

TypeinterventionalSponsorUniversity of MinnesotaRan2021 to 2022Enrolled412ConditionsHealth Knowledge, Attitudes, Practice, TrainingArmsComprehensive sexual health curriculum
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

B R Simon RosserDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300 S. 2nd St., #300, Minneapolis, MN, 55454, USA. rosser@umn.edu.
Nidhi KohliDepartment of Educational Psychology, University of Minnesota, 250 Education Sciences Bldg, 56 E River Rd, Minneapolis, MN, 55455, USA.
Alex J BatesDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300 S. 2nd St., #300, Minneapolis, MN, 55454, USA.
Kristine M C TalleyAdult and Gerontological Health, University of Minnesota School of Nursing School, 6-191 Weaver Densford Hall, 08 Harvard Street SE, Minneapolis, MN, 55455, USA.
Morgan M WrightDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300 S. 2nd St., #300, Minneapolis, MN, 55454, USA.
Elizabeth J PolterDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300 S. 2nd St., #300, Minneapolis, MN, 55454, USA.
Christopher W WheldonDepartment of Social and Behavioral Sciences, College of Public Health, Temple University, 1301 Cecil B. Moore Ave. Room 955, Philadelphia, PA, 19122, USA.
Ryan HaggartDepartment of Urology, University of Minnesota Medical School, Mayo Bldg, 420 Delaware St. Ste MMC 394, Minneapolis, MN, 55454, USA.
Daniel R DicksteinDepartment of Radiation Oncology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY, 10029, USA.
Michael W RossEli Coleman Institute for Sexual and Gender Health, Department of Family Medicine and Community Health,, University of Minnesota Medical School, 1300 S. 2nd St., Ste. 180, Minneapolis, MN, 55454, USA.
Ziwei ZhangDepartment of Educational Psychology, University of Minnesota, 250 Education Sciences Bldg, 56 E River Rd, Minneapolis, MN, 55455, USA.
William WestDepartment of Writing Studies, University of Minnesota, 213 Nolte Center, 315 Pillsbury Dr SE, Minneapolis, MN, 55455, USA.
Badrinath R KonetyAllina Health Cancer Institute, 800 E 28Th St, Minneapolis, MN, 55407, USA.

Funding

Minnesota Population Center Science and Technical CoreP2CHD041023 · NICHD · UNIVERSITY OF MINNESOTA · PI THERESA LOUISE OSYPUK · 2016 to 2026
$4.3M
Restore: Improving Sexual Outcomes of Gay and Bisexual Prostate Cancer SurvivorsR01CA218657 · NCI · UNIVERSITY OF MINNESOTA · PI ROSSER, B R SIMON · 2017 to 2021
$3.1M
Interdisciplinary Population Health Science Training: Linking Multilevel Forces Across TimeT32HD095134 · NICHD · UNIVERSITY OF MINNESOTA · PI THERESA LOUISE OSYPUK, John Robert Warren · 2019 to 2026
$2.5M
NCI NIH HHS 1R01CA218657NCI NIH HHS R01 CA218657NICHD NIH HHS P2C HD041023NICHD NIH HHS T32 HD095134
6 · The paper itself

Abstract

purposeSexual minority prostate cancer patients have worse health-related quality of life outcomes than heterosexual patients. We conducted the first study to test whether sexual and urinary rehabilitation tailored for sexual minority patients was acceptable, feasible, and efficacious at improving their sexual and urinary function.

methodsRestore-2 was a 24-month randomized controlled trial of an online biopsychobehavioral rehabilitation study for sexual minority men treated for prostate cancer experiencing sexual and/or urinary problems. Participants were 401 US sexual minority men treated for prostate cancer and experiencing sexual and/or urinary problems at baseline. Intervention components included phosphodiesterase-5 inhibitors, sexual aids, a pelvic floor exercise regimen and video, a guide to good gay sex following treatment, and coaching. Quality of life assessments were completed at baseline, 3, 6, 12, 18, and 24 months.

resultsWe confirmed good acceptability and feasibility, but only minimal improvement was observed over time and no differences were found between treatment and control arms.

conclusionsWe found no evidence that the intervention improved sexual or urinary outcomes for participants. However, we confirmed excellent acceptability and feasibility for a sexual rehabilitation program tailored to sexual minority participants. In addition, participants reported enduring usage and acceptability of sexual aids (including vacuum pump, anal dilators, and penile constriction rings) as well as masturbation and pelvic floor exercises to accommodate their sexual challenges. IMPLICATIONS FOR CANCER SURVIVORS: Sexual "accommodation," rather than "rehabilitation," may be a more accurate and realistic goal for this population. Patients should be provided sexual aids to help accommodate their sexual and urinary challenges.

trial registrationThis study was retrospectively registered with ClinicalTrials.gov, study number: NCT03923582; date: 22/04/2019.

Indexed as

Homosexuality, MaleProstatic NeoplasmsSexual and Gender MinoritiesAgedFeasibility StudiesHumansMaleMiddle AgedQuality of LifeHealth care disparityHealth status disparitiesProstatic neoplasmsSexual dysfunction, PhysiologicalSexual minorities

Identifiers

PMID39266938
PMCPMC13166964

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.