Evidence map›Paper›PMID 39266931›Full record

Trial reportJournal of nephrology2024

Education and cooking methods in the management of calcium and PTH serum levels in patients on hemodialysis: a randomized controlled study.

Ivica Vrdoljak, Anja Pozaić, Martina Bituh, Ninoslav Leko, Tea Vrdoljak Margeta, Draško Pavlović, Ines Panjkota Krbavčić

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ivica VrdoljakDepartment of Dietetics and Nutrition, General Hospital "Dr Josip Benčević", Andrije Štampara 42, 35 000, Slavonski Brod, Croatia.
Anja PozaićFaculty of Food Technology and Biotechnology, Department of Food Quality Control, University of Zagreb, Pierottijeva 6, 10 000, Zagreb, Croatia. avukomanovic@pbf.hr.ORCID 0000-0002-1559-0766
Martina BituhFaculty of Food Technology and Biotechnology, Department of Food Quality Control, University of Zagreb, Pierottijeva 6, 10 000, Zagreb, Croatia.ORCID 0000-0002-3596-8383
Ninoslav LekoDepartment of Nephrology and Dialysis, General Hospital "Dr Josip Benčević", Andrije Štampara 42, 35 000, Slavonski Brod, Croatia.
Tea Vrdoljak MargetaDepartment of Nephrology and Dialysis, General Hospital "Dr Josip Benčević", Andrije Štampara 42, 35 000, Slavonski Brod, Croatia.
Draško PavlovićPolyclinic for Internal Medicine and Dialysis B.Braun Avitum, Hondlova 2/11, 10 000, Zagreb, Croatia.ORCID 0000-0002-2380-869X
Ines Panjkota KrbavčićFaculty of Food Technology and Biotechnology, Department of Food Quality Control, University of Zagreb, Pierottijeva 6, 10 000, Zagreb, Croatia.ORCID 0000-0003-3201-3837

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease associated mineral bone disorder (CKD-MBD) is one of the major causes of excess morbidity and mortality in hemodialysis patients. The purpose of this study was to investigate whether education about dietary intakes and specific food processing methods affect serum calcium and PTH concentrations in hemodialysis patients.

methodsForty-seven hemodialysis patients were randomly divided into a control and an intervention group. All participants were on individualized phosphate binder therapy. Both groups received education on dietary intake by a trained dietitian. The intervention group received additional education on specific preparation methods of different foodstuffs and consumed two hospital meals prepared according to these methods during hemodialysis. Serum calcium and PTH levels, and vitamin D analog therapy dosage were periodically monitored during the 1-year study period.

resultsAt the baseline of the study, there were no differences between control and intervention groups in serum calcium (p = 0.078), serum PTH (p = 0.670), and vitamin D analog therapy dosage (p = 0.184). At the end of the study, serum calcium was better regulated in the intervention group, resulting in a significant difference between the study groups (p = 0.013). This was also confirmed by serum PTH levels in the intervention group, which remained stable until the end of the study (p = 0.110). DISCUSSION: Additional education on specific food processing techniques may result in improved management of serum calcium and PTH levels, which could ultimately provide better control of secondary hyperparathyroidism in hemodialysis patients.

Indexed as

CalciumParathyroid HormonePatient Education as TopicRenal DialysisVitamin DAdultAgedChronic Kidney Disease-Mineral and Bone DisorderCookingFemaleHumansMaleMiddle AgedTreatment OutcomeCalciumParathyroid HormonePTH protein, humanVitamin DCalciumHemodialysisPTHVitamin D

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.