Evidence map›Paper›PMID 39266665›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

Standardizing the diagnosis of necrotizing enterocolitis in infants with congenital heart disease.

Margot Hillyer, Michael Fundora, Feifei Williams, Michelle Gleason, Mary Lukacs, Shannon Hamrick, Jonathan Meisel, Shanelle Clarke, Natalie Korcinsky-Tillman, Nikhil Chanani

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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Margot HillyerEmory University School of Medicine, Department of Pediatrics, Division of Critical Care Medicine, Atlanta, GA, USA. margot.hillyer@emory.edu.ORCID http://orcid.org/0000-0003-3389-6328
Michael FundoraEmory University School of Medicine, Department of Pediatrics, Division of Cardiology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-3204-1176
Feifei WilliamsEmory University School of Medicine, Department of Pediatrics, Division of Cardiology, Atlanta, GA, USA.
Michelle GleasonThe Heart Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Mary LukacsThe Heart Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Shannon HamrickEmory University School of Medicine, Department of Pediatrics, Division of Neonatology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-6294-3480
Jonathan MeiselEmory University School of Medicine, Department of Pediatrics, Division of General Surgery, Atlanta, GA, USA.
Shanelle ClarkeEmory University School of Medicine, Department of Pediatrics, Division of Cardiology, Atlanta, GA, USA.
Natalie Korcinsky-TillmanThe Heart Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Nikhil ChananiEmory University School of Medicine, Department of Pediatrics, Division of Cardiology, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis quality improvement initiative aimed to standardize the diagnosis of necrotizing enterocolitis (NEC) in infants with congenital heart disease (CHD). STUDY

designA multidisciplinary team developed clinical practice guidelines for the diagnosis and treatment of NEC within the Cardiac Intensive Care Unit (CICU). The diagnosis rate of NEC per 100 at-risk admissions was the primary outcome measure. NEC order set usage was employed as a process measure, and the balancing measures monitored were CICU length of stay (LOS) and mortality.

resultAfter guideline development and implementation, the diagnosis rate of NEC decreased from 3% to 1%, sustained over three years. The EMR order set enabled guideline integration into daily workflow. No change was noted in CICU LOS or mortality.

conclusionGuideline implementation standardized the diagnosis of NEC in infants with CHD. Establishing a standardized definition and subsequent treatment regimen has enabled us to provide more consistent and appropriate care.

Indexed as

Enterocolitis, NecrotizingHeart Defects, CongenitalPractice Guidelines as TopicFemaleHumansInfantInfant, NewbornIntensive Care Units, NeonatalLength of StayMaleQuality Improvement

Identifiers

PMID39266665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.