Evidence map›Paper›PMID 39266613›Full record

ArticleScientific reports2024

Clinical utility of rapid on-site evaluation of brush cytology during bronchoscopy using endobronchial ultrasound with a guide sheath.

Kazuhiro Nishiyama, Kei Morikawa, Shotaro Kaneko, Makoto Nishida, Aya Matsushima, Yoshihiro Nishi, Yu Numata, Yusuke Shinozaki, Hajime Tsuruoka, Hirotaka Kida and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kazuhiro NishiyamaDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan. kazuhiro.nishiyama@marianna-u.ac.jp.
Kei MorikawaDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Shotaro KanekoDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Makoto NishidaDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Aya MatsushimaDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Yoshihiro NishiDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Yu NumataDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Yusuke ShinozakiDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Hajime TsuruokaDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Hirotaka KidaDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Hiroshi HandaDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Naoki ShimadaDepartment of Pathology, St. Marianna University Hospital, Kawasaki, Japan.
Chie OkawaDepartment of Pathology, St. Marianna University Hospital, Kawasaki, Japan.
Nobuyuki OhikeDepartment of Pathology, St. Marianna University School of Medicine, Kawasaki, Japan.
Junki KoikeDepartment of Pathology, St. Marianna University School of Medicine, Kawasaki, Japan.
Masamichi MineshitaDepartment of Respiratory Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have shown that rapid on-site evaluation (ROSE) improves the diagnostic yield of bronchoscopy using endobronchial ultrasound with a guide sheath (EBUS-GS) for peripheral pulmonary lesions (PPL). While ROSE of imprint cytology from forceps biopsy has been widely discussed, there are few reports on ROSE of brush cytology. This study investigated the utility of ROSE of brush cytology during bronchoscopy. We retrospectively analyzed data from 214 patients who underwent bronchoscopy with EBUS-GS for PPL. The patients in the ROSE group had significantly higher diagnostic sensitivity through the entire bronchoscopy process than in the non-ROSE group (96.8% vs. 83.3%, P = 0.002). The use of ROSE significantly increased the sensitivity of brush cytology with Papanicolaou staining (92.9% vs. 75.0%, P < 0.001). When ROSE was sequentially repeated on brushing specimens, initially negative ROSE results converted to positive in 79.5% of cases, and the proportion of specimens with high tumor cell counts increased from 42.1 to 69.0%. This study concludes that ROSE of brush cytology improves the diagnostic accuracy of bronchoscopy and enhances specimen quality through repeated brushing.

Indexed as

BronchoscopyLung NeoplasmsAdultAgedAged, 80 and overCytodiagnosisEndosonographyFemaleHumansMaleMiddle AgedRapid On-site EvaluationRetrospective StudiesSensitivity and SpecificityBrushingEndobronchial ultrasound with a guided sheathPeripheral lung lesionsRapid on-site evaluation

Identifiers

PMID39266613
PMCPMC11392937

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.