DAMM for the detection and tracking of multiple animals within complex social and environmental settings.

Accurate detection and tracking of animals across diverse environments are crucial for studying brain and behavior. Recently, computer vision techniques have become essential for high-throughput behavioral studies; however, localizing animals in complex conditions remains challenging due to intra-class visual variability and environmental diversity. These challenges hinder studies in naturalistic settings, such as when animals are partially concealed within nests. Moreover, current tools are laborious and time-consuming, requiring extensive, setup-specific annotation and training procedures. To address these challenges, we introduce the 'Detect-Any-Mouse-Model' (DAMM), an object detector for localizing mice in complex environments with minimal training. Our approach involved collecting and annotating a diverse dataset of single- and multi-housed mice in complex setups. We trained a Mask R-CNN, a popular object detector in animal studies, to perform instance segmentation and validated DAMM's performance on a collection of downstream datasets using zero-shot and few-shot inference. DAMM excels in zero-shot inference, detecting mice and even rats, in entirely unseen scenarios and further improves with minimal training. Using the SORT algorithm, we demonstrate robust tracking, competitive with keypoint-estimation-based methods. Notably, to advance and simplify behavioral studies, we release our code, model weights, and data, along with a user-friendly Python API and a Google Colab implementation.