Evidence map›Paper›PMID 39266559›Full record

ArticleScientific data2024

A comprehensive IDA and SWATH-DIA Lipidomics and Metabolomics dataset: SARS-CoV-2 case control study.

Ammar Tahir, Agnes Draxler, Tamara Stelzer, Amelie Blaschke, Brenda Laky, Marton Széll, Jessica Binar, Viktoria Bartak, Laura Bragagna, Lina Maqboul and 3 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ammar TahirDepartment of Pharmaceutical Sciences, Division of Pharmacognosy, University of Vienna, Vienna, Austria. ammar.tahir@univie.ac.at.ORCID 0000-0003-3682-5680
Agnes DraxlerDepartment of Nutritional Sciences, University of Vienna, Vienna, Austria.
Tamara StelzerDepartment of Nutritional Sciences, University of Vienna, Vienna, Austria.
Amelie BlaschkeKlinik Donaustadt, Emergency Department, Vienna, Austria.
Brenda LakyMedical University of Vienna, Vienna, Austria.
Marton SzéllKlinik Donaustadt, Emergency Department, Vienna, Austria.
Jessica BinarSection of Biomedical Sciences, Department of Health Sciences, FH Campus Wien, University of Applied Sciences, Vienna, Austria.
Viktoria BartakDepartment of Nutritional Sciences, University of Vienna, Vienna, Austria.
Laura BragagnaDepartment of Nutritional Sciences, University of Vienna, Vienna, Austria.
Lina MaqboulDepartment of Nutritional Sciences, University of Vienna, Vienna, Austria.ORCID 0009-0000-6080-886X
Theresa HerzogKlinik Donaustadt, Emergency Department, Vienna, Austria.
Rainer ThellKlinik Donaustadt, Emergency Department, Vienna, Austria.
Karl-Heinz WagnerDepartment of Nutritional Sciences, University of Vienna, Vienna, Austria.ORCID 0000-0002-1683-7265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A significant hurdle in untargeted lipid/metabolomics research lies in the absence of reliable, cross-validated spectral libraries, leading to a considerable portion of LC-MS features being labeled as unknowns. Despite continuous advancement in annotation tools and libraries, it is important to safeguard, publish and share acquired data through public repositories. Embracing this trend of data sharing not only promotes efficient resource utilization but also paves the way for future repurposing and in-depth analysis; ultimately advancing our comprehension of Covid-19 and other diseases. In this work, we generated an extensive MS-dataset of 39 Covid-19 infected patients versus age- and gender-matched 39 healthy controls. We implemented state of the art acquisition techniques including IDA and SWATH-DIA to ensure a thorough insight in the lipidome and metabolome, ensuring a repurposable dataset.

Indexed as

COVID-19LipidomicsMetabolomicsSARS-CoV-2Case-Control StudiesChromatography, LiquidFemaleHumansMaleMass SpectrometryMetabolome

Identifiers

PMID39266559
PMCPMC11393081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.