Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
5 authors.
Logan S SchwartzThe Jackson Laboratory, Bar Harbor, ME, USA.
Ruth L SaxlThe Jackson Laboratory, Bar Harbor, ME, USA.
Tim StearnsThe Jackson Laboratory, Bar Harbor, ME, USA.
Maria TelpoukhovskaiaThe Jackson Laboratory, Bar Harbor, ME, USA. maria.telpoukhovskaia@jax.org.ORCID 0000-0002-5237-4042
Jennifer J TrowbridgeThe Jackson Laboratory, Bar Harbor, ME, USA. Jennifer.trowbridge@jax.org.ORCID 0000-0002-7636-9504
Funding
Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI Paul Robson · 1985 to 2026
$61.9M
Developing Effective Approaches to Extend Hematopoietic Healthspan by Targeting Cell-Extrinsic and Cell-Intrinsic Alterations at Middle AgeR01DK118072 · NIDDK · JACKSON LABORATORY · PI Jennifer Jean Trowbridge · 2018 to 2026
$4.2M
Inflammatory Signaling in DNMT3A-Mutated Human Hematopoietic Stem CellsU01AG077925 · NIA · JACKSON LABORATORY · PI LEVINE, ROSS L, TROWBRIDGE, JENNIFER JEAN · 2021 to 2025
$2.9M
Discovery of Aging-Associated Mechanisms Causing Expansion and Progression of Clonal Hematopoiesis of Indeterminant Potential (CHIP)R01AG069010 · NIA · JACKSON LABORATORY · PI TROWBRIDGE, JENNIFER JEAN · 2020 to 2024
$2.4M
The role of the aged BM microenvironment in accelerating Dnmt3a mutant clonal hematopoiesisF31DK127573 · NIDDK · TUFTS UNIVERSITY BOSTON · PI SCHWARTZ, LOGAN SARI · 2020 to 2022
$126k
NCI NIH HHS P30 CA034196NIA NIH HHS R01 AG069010NIA NIH HHS U01 AG077925NIDDK NIH HHS F31 DK127573NIDDK NIH HHS R01 DK118072U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) P30CA034196U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) F31DK127573U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R01DK118072U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) U01AG077925
6 · The paper itself
Abstract
Oncostatin M (OSM) is a member of the interleukin-6 (IL-6) family of cytokines and has been found to have anti-inflammatory and pro-inflammatory properties in various cellular and disease contexts. OSM signals through two receptor complexes, one of which includes OSMRβ. Here, we investigated OSM-OSMRβ signaling in adult mouse hematopoietic stem cells (HSCs) using the conditional Osmr
Indexed as
Hematopoietic Stem CellsOncostatin MSignal TransductionAnimalsMiceOncostatin M Receptor beta SubunitReceptors, Oncostatin MRNA-SeqSequence Analysis, RNAOncostatin MOncostatin M Receptor beta SubunitReceptors, Oncostatin M
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Oncostatin M receptor-dependent signaling assessed by RNA sequencing in mouse hematopoietic stem cells. · full record | OpenQuestion