ArticleNature communications2024
Hybrid lipid-AuNP clusters as highly efficient SERS substrates for biomedical applications.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Electron-Donating Benzenethiols Direct Rapid Formation of Plasmonic Gold Nanoflowers.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Emerging Plasmonic Nanomaterials for SERS-Based Disease Diagnostics: Innovations, Clinical Challenges, and AI Integration.Molecules (Basel, Switzerland) · 2026Review
- In vivo dynamic hotspot-enhanced Raman spectroscopy via reconfigurable swarming nanoprobes.Nature communications · 2026Article
- Deep learning-assisted SERS for detection of propoxate and isopropoxate in E-cigarettes.RSC advances · 2026Article
- Self-Assembled Rhodium Nanoantennas for Single-Protein UV SERS.Nanophotonics (Berlin, Germany) · 2026Article
- SERS-Based Nano- and Microsystems Toward Biomedical Applications.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Machine learning-enhanced identification of fluorophilic interactions for improved SERS detection of PFOA.Environmental science. Nano · 2026Article
- From nanotags to precision biomedicine: SERS-driven progress and innovation in tumor biomarker profiling, dynamic bioimaging, AI-enhanced diagnostics and therapy.Theranostics · 2026Review
- Medical importance and pharmacokinetics of gold nanoparticles in the human body.Molecular cancer · 2025Review
- Engineering nanopore in monolayer WSScience advances · 2025Article
- Astrocyte Autophagy in Neurodegenerative Diseases: Current Progress in Mechanisms and Therapeutics.Neurochemical research · 2025Review
- Gradient Nanostructures and Machine Learning Synergy for Robust Quantitative Surface-Enhanced Raman Scattering.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Nanoplasmonic Isosbestics Uncover Mesoscale Assembly of Gold Nanoparticles on Soft Templates.Journal of the American Chemical Society · 2025Article
- Grating/microcavity arrays on lily petal replicas as dual-functional SERS substrates for rapid monitoring of thiram on fruit surface and malachite green in surface water.Mikrochimica acta · 2025Article
- A state-of-the-art review of the recent advances of theranostic liposome hybrid nanoparticles in cancer treatment and diagnosis.Cancer cell international · 2025Review
- Hot-spot empowered gold nanoparticles for theranostics in breast cancer.Theranostics · 2025Review
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although Surface Enhanced Raman Scattering (SERS) is widely applied for ultrasensitive diagnostics and imaging, its potential is largely limited by the difficult preparation of SERS tags, typically metallic nanoparticles (NPs) functionalized with Raman-active molecules (RRs), whose production often involves complex synthetic approaches, low colloidal stability and poor reproducibility. Here, we introduce LipoGold Tags, a simple platform where gold NPs (AuNPs) clusters form via self-assembly on lipid vesicle. RRs embedded in the lipid bilayer experience enhanced electromagnetic field, significantly increasing their Raman signals. We modulate RRs and lipid vesicle concentrations to achieve optimal SERS enhancement and we provide robust structural characterization. We further demonstrate the versatility of LipoGold Tags by functionalizing them with biomolecular probes, including antibodies. As proof of concept, we successfully detect intracellular GM1 alterations, distinguishing healthy donors from patients with infantile GM1 gangliosidosis, showcasing LipoGold Tags as advancement in SERS probes production.
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Registered trials
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