Observational studyBritish journal of anaesthesia2024
Association between inspired oxygen fraction and development of postoperative pulmonary complications in thoracic surgery: a multicentre retrospective cohort study.
Observational study in British journal of anaesthesia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Effects of FiO2 adjustment on hyperoxia biomarkers and postoperative complications using oxygen reserve index during one-lung ventilation.BMC anesthesiology · 2026Trial
- Dexmedetomidine reduces pulmonary complications in older patients undergoing abdominal laparoscopic surgery: a prospective, single-blinded, randomized controlled trial.BMC anesthesiology · 2026Trial
- The impact of varying intraoperative oxygen concentrations on lung ultrasound scores and postoperative recovery among elderly patients residing in moderate altitude areas during laparoscopic surgery.Frontiers in physiology · 2026Trial
- Plasma Lipidomics Identify Pathways Linked to Acute Lung Injury in a Porcine One-Lung Ventilation Surgery Model.International journal of molecular sciences · 2026Article
- Association between intraoperative inspired oxygen exposure and risk of postoperative pulmonary complications in abdominal surgery: a multi-center prospective cohort study.Journal of anesthesia · 2026Article
- Risk factors, pathogenesis, and botanical drugs interventions for postoperative pulmonary complications after cardiothoracic surgery: a narrative review.Journal of thoracic disease · 2026Review
- Video double-lumen endotracheal tube reduces hypoxemia during one-lung ventilation in thoracoscopic surgery: a prospective randomized controlled trial.Journal of thoracic disease · 2026Article
- Risk factors and prediction model for acute respiratory distress syndrome in patients with digestive tumor after surgery.World journal of gastrointestinal surgery · 2026Article
- FiOFrontiers in medicine · 2026Article
- Tailored single-lung ventilation approaches and postoperative pulmonary outcomes in thoracic surgery.Journal of thoracic disease · 2025Review
- The curative effect analysis of simultaneous U-VATS for bilateral multiple primary early-stage lung cancers.Frontiers in oncology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundLimited data exist to guide oxygen administration during one-lung ventilation for thoracic surgery. We hypothesised that high intraoperative inspired oxygen fraction during lung resection surgery requiring one-lung ventilation is independently associated with postoperative pulmonary complications (PPCs).
methodsWe performed this retrospective multicentre study using two integrated perioperative databases (Multicenter Perioperative Outcomes Group and Society of Thoracic Surgeons General Thoracic Surgery Database) to study adult thoracic surgical procedures using one-lung ventilation. The primary outcome was a composite of PPCs (atelectasis, acute respiratory distress syndrome, pneumonia, respiratory failure, reintubation, and prolonged ventilation >48 h). The exposure of interest was high inspired oxygen fraction (FiO
resultsAcross four US medical centres, 141/2733 (5.2%) procedures conducted in 2716 patients (55% female; mean age 66 yr) resulted in PPCs. FiO
conclusionsOur results do not support limiting the inspired oxygen fraction for the purpose of reducing postoperative pulmonary complications in thoracic surgery involving one-lung ventilation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.