Evidence map›Paper›PMID 39266399›Full record

ArticleInternational dental journal2025

Effect of Experimental Bleaching Gels With Enzymes on Composite and Enamel.

Amalia Moldovan, Stanca Cuc, Cristina Gasparik, Codruța Sarosi, Marioara Moldovan, Nicoleta Ilie, Ioan Petean, Laura Monica Rusu, Andrei Ionescu, Mihaela Pastrav

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amalia MoldovanPhysics and Chemistry Department, Technical University of Cluj-Napoca, Cluj-Napoca, Romania.
Stanca Cuc"Raluca Ripan" Institute of Research in Chemistry, "Babes Bolyai" University, Cluj-Napoca, Romania. Electronic address: stanca.boboia@ubbcluj.ro.
Cristina GasparikDepartment of Prosthetic Dentistry and Dental Materials, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Codruța Sarosi"Raluca Ripan" Institute of Research in Chemistry, "Babes Bolyai" University, Cluj-Napoca, Romania.
Marioara Moldovan"Raluca Ripan" Institute of Research in Chemistry, "Babes Bolyai" University, Cluj-Napoca, Romania. Electronic address: marioara.moldovan@ubbcluj.ro.
Nicoleta IlieDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig - Maximilians - University, Munich, Germany.
Ioan PeteanFaculty of Chemistry and Chemical Engineering, "Babes-Bolyai" University, Cluj-Napoca, Romania.
Laura Monica RusuDepartment of Dental Materials, Faculty of Dental Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Andrei IonescuDepartment of Biomedical, Surgical and Dental Sciences, Oral Microbiology and Biomaterials Laboratory, Università Degli Studi di Milano, Milano, Italy.
Mihaela PastravDepartment of Orthodontics, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

aimsPotential secondary or toxic effects of peroxide-based whitening gels have driven the search for alternative methods that use natural compounds with gentle action on tooth enamel that provide remineralizing benefits.

methodsThis study introduces four innovative experimental whitening gels (GC, G1, G3, G4) formulated with enzymes (Bromelaine and Papaine) and natural extracts, along with SiO

resultsCoffee and natural juice stains significantly increase the roughness of composite and enamel surfaces by forming deposits. The enzymatic action of bromelain and papain effectively disorganizes and removes these clusters, significantly reducing surface roughness.

conclusionNotably, the gel containing papain and nanostructured SiO

Indexed as

BromelainsComposite ResinsDental EnamelPapainTooth BleachingTooth Bleaching AgentsAnti-Bacterial AgentsCoffeeDental PulpEscherichia coliGelsHumansMicroscopy, Atomic ForceMicroscopy, Electron, ScanningSilicon DioxideStreptococcus mutansAnti-Bacterial AgentsBromelainsCoffeeComposite ResinsGelsPapainSilicon DioxideTooth Bleaching AgentsBleaching gelBromelainPapainStains removal

Identifiers

PMID39266399
PMCPMC11976588

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.