Evidence map›Paper›PMID 39266315›Full record

ArticleBMJ open2024

Effects of yoga compared with health promotion on health-related quality of life in adults with post-COVID-19 condition: protocol for a randomised controlled trial.

Mikaela Brodén, Paul Welfordsson, Maria Niemi, Vinod Diwan, Komal Shah, Vijayakumar Pattanadara, Mats Hallgren

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mikaela BrodénDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID 0009-0004-0261-8434
Paul WelfordssonDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-9147-783X
Maria NiemiDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-5407-6981
Vinod DiwanDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-5831-2037
Komal ShahIndian Institute of Public Health, Public Health Foundation of India, Gandhinagar, Gujarat, India.ORCID 0000-0003-0866-2386
Vijayakumar PattanadaraDepartment of Integrative Medicine, Sduaher, Kolar, Karnataka, India.
Mats HallgrenDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden mats.hallgren@ki.se.ORCID 0000-0002-0599-2403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPost-COVID-19 condition (post COVID, also known as long COVID) is a global public health issue estimated to affect over 100 million people. Common symptoms include fatigue, dyspnoea and cognitive dysfunction ('brain fog'). Over time, these symptoms have an adverse effect on mental health, physical activity and quality of life (QoL). The condition requires innovative and feasible treatment approaches that can be effective and self-managed. Physical activity is essential for good health; however, aerobic exercise or weightlifting may not be suitable for post COVID patients who experience fatigue or breathlessness. The benefits of yoga include improved flexibility, mobility, body strength and balance. It is also shown to reduce symptoms of fatigue and improve breathing efficiency, mental health and QoL. This study protocol describes the rationale and methods for a randomised controlled trial (RCT) of a yoga-based intervention designed for adults with post COVID. METHODS AND ANALYSIS: A two-group, parallel, RCT with blinded follow-up assessments. Participants will be randomised with a 1:1 allocation to either a 12-week yoga-based intervention or a 12-week health promotion (active comparison) intervention. In total, 88 participants aged 30-65 years will be recruited and randomised. The primary outcome is health-related QoL (36-item Short-Form). Secondary outcomes are dyspnoea, fatigue, sleep quality, cognitive functions, mental fatigue, depression, anxiety, physical activity, demographic data and physical health measures. Data will be analysed as intention-to-treat basis, using linear mixed modelling. All assessments are conducted at Karolinska Institutet in Stockholm, Sweden. The yoga-based intervention will take place at a yoga studio centrally located in Stockholm city. ETHICS AND DISSEMINATION: The study is approved by the Swedish Ethical Review Authority, reference number 2023/06518-01. All participants must sign written informed consent before enrolment and are free to withdraw from the study at any point. Key results will be available through research articles and seminars. TRIAL REGISTRATION NUMBER: German Clinical Trials Register, DRKS00032837.

Indexed as

COVID-19Health PromotionQuality of LifeYogaAdultExerciseFatigueFemaleHumansMaleMiddle AgedPost-Acute COVID-19 SyndromeRandomized Controlled Trials as TopicSARS-CoV-2FatigueMENTAL HEALTHPost-Acute COVID-19 SyndromePUBLIC HEALTHQuality of LifeRandomized Controlled Trial

Identifiers

PMID39266315
PMCPMC11404200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.