Evidence map›Paper›PMID 39265976›Full record

ArticleHamostaseologie2026

Perioperative Management for Port Catheter Procedures in Pediatric Patients with Severe Hemophilia and Inhibitors.

Anna Woestemeier, Silvia Horneff, Vincent Marlon Lüder, Jennifer Nadal, Arne Koscielny, Jörg C Kalff, Johannes Oldenburg, Georg Goldmann, Philipp Lingohr

Abstract read
In one paragraph

Article in Hamostaseologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna WoestemeierDepartment for General, Visceral, Thoracic and Vascular Surgery, University Hospital of Bonn, Bonn, Germany.
Silvia HorneffInstitute of Experimental Haematology and Transfusions Medicine, University Hospital of Bonn, Bonn, Germany.
Vincent Marlon LüderDepartment for General, Visceral, Thoracic and Vascular Surgery, University Hospital of Bonn, Bonn, Germany.
Jennifer NadalInstitute for Medical Biometrics, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany.
Arne KoscielnyDepartment for General and Visceral Surgery, St. Elisabeth-Hospital Leipzig, Leipzig, Germany.
Jörg C KalffDepartment for General, Visceral, Thoracic and Vascular Surgery, University Hospital of Bonn, Bonn, Germany.
Johannes OldenburgInstitute of Experimental Haematology and Transfusions Medicine, University Hospital of Bonn, Bonn, Germany.
Georg GoldmannInstitute of Experimental Haematology and Transfusions Medicine, University Hospital of Bonn, Bonn, Germany.
Philipp LingohrDepartment for General, Visceral, Thoracic and Vascular Surgery, University Hospital of Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The objective of this systematic study was to assess the perioperative management and outcome of surgery in pediatric patients with hemophilia A/B and inhibitors compared to nonhemophilic pediatric patients. Methods: The surgical outcome of 69 port catheter operations in patients with hemophilia who developed inhibitory antibodies against the administered factor was compared to 51 procedures in the control group. In the patients with hemophilia and inhibitors, a standardized protocol for recombinant activated factor VII was used to prevent perioperative bleeding. Results: Hemophilic pediatric patients with inhibitors showed no significant differences in perioperative management (blood transfusion: Conclusion: This study has demonstrated that port catheter insertion and removal is safe in these patients. Moreover, it shows the importance of a coordinated approach with a multidisciplinary team.

Indexed as

Hemophilia APerioperative CareAdolescentChildChild, PreschoolFactor VIIaFemaleHumansInfantLength of StayMaleRecombinant ProteinsTreatment OutcomeFactor VIIaRecombinant Proteins

Identifiers

PMID39265976
PMCPMC13099173

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.