ArticleCell genomics2024
Long genetic and social isolation in Neanderthals before their extinction.
Article in Cell genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Article
- Regulation of NAT1 activity in modern humans by a novel phosphorylation site.Science advances · 2026Article
- A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Archaeogenetic insights into the demographic history of Late Neanderthals.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Recent advances in methods to characterize archaic introgression in modern humans.Genome research · 2026Review
- Archaic humans in the Middle Palaeolithic Levant conducted planned and selective intercepts of aurochs, but not mass hunting.Scientific reports · 2025Article
- A simple analytical model for Neanderthal disappearance due to genetic dilution by recurrent small-scale immigrations of modern humans.Scientific reports · 2025Article
- AdDeam: a fast and scalable tool for estimating and clustering reference-level damage profiles.Bioinformatics (Oxford, England) · 2025Article
- Muscle AMP deaminase activity was lower in Neandertals than in modern humans.Nature communications · 2025Article
- An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis.Cell genomics · 2025Article
- Reconciling Species Concepts: An Ecological Perspective.American journal of biological anthropology · 2025Article
- Semicircular canals shed light on bottleneck events in the evolution of the Neanderthal clade.Nature communications · 2025Article
- Buca della Iena and Grotta del Capriolo: New chronological, lithic, and faunal analyses of two late Mousterian sites in Central Italy.PloS one · 2025Article
- Arrow heads at Obi-Rakhmat (Uzbekistan) 80 ka ago?PloS one · 2025Article
- The cost of language: functionally over-dominant language circuits in the human brain may limit cognitive abilities and non-verbal executive functions.Frontiers in human neuroscience · 2025Article
- Art beyond cognition: reframing Neanderthal art through social connectivity and cultural transmission.Evolutionary human sciences · 2025Article
- Use it or lose it: A model-based assessment of the hypothesis that European Neanderthals relied on wildfires to create their campfires.Open research Europe · 2025Article
- Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans.Science (New York, N.Y.) · 2024Article
- How (and why) languages became more complex as we evolved more prosocial: the human self-domestication view.Frontiers in psychology · 2024Article
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Authors and funding
23 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Neanderthal genomes have been recovered from sites across Eurasia, painting an increasingly complex picture of their populations' structure that mostly indicates that late European Neanderthals belonged to a single metapopulation with no significant evidence of population structure. Here, we report the discovery of a late Neanderthal individual, nicknamed "Thorin," from Grotte Mandrin in Mediterranean France, and his genome. These dentognathic fossils, including a rare example of distomolars, are associated with a rich archeological record of Neanderthal final technological traditions in this region ∼50-42 thousand years ago. Thorin's genome reveals a relatively early divergence of ∼105 ka with other late Neanderthals. Thorin belonged to a population with a small group size that showed no genetic introgression with other known late European Neanderthals, revealing some 50 ka of genetic isolation of his lineage despite them living in neighboring regions. These results have important implications for resolving competing hypotheses about causes of the disappearance of the Neanderthals.
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