Evidence map›Paper›PMID 39265426›Full record

ArticleInternational journal of hygiene and environmental health2025

Prenatal and early life exposure to fine particulate matter and telomere length in early childhood.

Jesephat Edzie, Cecilia Alcala, Tessa R Bloomquist, Ivan Gutierrez-Avila, Allan C Just, Vishal Midya, Martha María Téllez Rojo, Guadalupe Estrada-Gutierrez, Rosalind J Wright, Robert O Wright and 2 more

Abstract read
In one paragraph

Article in International journal of hygiene and environmental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jesephat EdzieDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, USA.
Cecilia AlcalaDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, USA.
Tessa R BloomquistDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, USA.
Ivan Gutierrez-AvilaDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, USA.
Allan C JustDepartment of Epidemiology, Brown University School of Public Health, USA.
Vishal MidyaDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, USA.
Martha María Téllez RojoCenter for Nutrition and Health Research, National Institute of Public Health, Ministry of Health, Cuernavaca, Morelos, Mexico.
Guadalupe Estrada-GutierrezClinical Research Branch, National Institute of Perinatology, Mexico City, Mexico.
Rosalind J WrightDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, USA; Department of Public Health, Icahn School of Medicine at Mount Sinai, USA; Institute for Climate Change, Environmental Health, and Exposomics, Icahn School of Medicine at Mount Sinai, USA.
Robert O WrightDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, USA; Department of Public Health, Icahn School of Medicine at Mount Sinai, USA; Institute for Climate Change, Environmental Health, and Exposomics, Icahn School of Medicine at Mount Sinai, USA.
Andrea A BaccarelliDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, USA.
Maria José RosaDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, USA. Electronic address: maria.rosa@mssm.edu.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Chris Gennings · 2014 to 2026
$21.3M
Stress, Lead, Iron Deficiency and NeurodevelopmentR01ES013744 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Robert O Wright · 2007 to 2026
$13.4M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
BPA, Phthalates & Stress: Mechanisms and Interactions for Childhood ObesityR01ES021357 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BACCARELLI, ANDREA, WRIGHT, ROBERT O · 2012 to 2016
$3.3M
Metal Mixtures and NeurodevelopmentR01ES014930 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROBERT O · 2006 to 2010
$3.2M
Effect of Perinatal Exposure to Metals on Lung Function Trajectories and Mitochondrial DNA Heteroplasmy from Childhood to AdolescenceR01ES033245 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Maria Jose Rosa · 2022 to 2026
$3.0M
The Programming Research in Obesity, GRowth, Environment and Social Stress (PROGRESS) CohortR24ES028522 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Megan K Horton, Maria Jose Rosa · 2017 to 2026
$1.8M
Ambient Air Pollution, Stress, Oxidative Markers and Respiratory Health in Mexican ChildrenR00ES027496 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ROSA, MARIA JOSE · 2019 to 2021
$743k
The Programming Research in Obesity, GRowth, Environment and Social Stress (PROGRESS) CohortU24ES028522 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HORTON, MEGAN K, ROSA, MARIA JOSE · 2024 to 2025
$719k
A Community Partnered Approach to Assessing the Impact of Prenatal Pesticide Exposure on Child Respiratory Outcomes in Mexico CityK99ES035894 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALCALA, CECILIA SARA · 2024 to 2024
$106k
NCATS NIH HHS UL1 TR004419NICHD NIH HHS T32 HD049311NIEHS NIH HHS K99 ES035894NIEHS NIH HHS L40 ES034609NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R00 ES027496NIEHS NIH HHS R01 ES013744NIEHS NIH HHS R01 ES014930NIEHS NIH HHS R01 ES021357NIEHS NIH HHS R01 ES033245NIEHS NIH HHS R24 ES028522NIEHS NIH HHS U24 ES028522
6 · The paper itself

Abstract

backgroundTelomere length is a biomarker of molecular aging that may be impacted by air pollution exposure starting in utero. We aimed to examine the association between prenatal and early life exposure to fine particulate matter (PM

methodsAnalyses included 384 mother-child pairs enrolled in the Programming Research in Obesity, Growth, and Environmental Stressors (PROGRESS) birth cohort in Mexico City. Exposure to PM

resultsIn trimester specific models, we found an association between 2nd trimester PM

conclusionSecond trimester PM

Indexed as

Air PollutantsParticulate MatterPrenatal Exposure Delayed EffectsAdultChildChild, PreschoolEnvironmental ExposureFemaleHumansLeukocytesMaleMaternal ExposureMexicoPregnancyTelomereAir PollutantsParticulate MatterEarly life exposureParticulate matterPrenatal exposureSex-specific effectsTelomere length

Identifiers

PMID39265426
PMCPMC11624059

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.