Evidence map›Paper›PMID 39264810›Full record

ArticleCell reports2024

Unraveling the phenotypic states of human innate-like T cells: Comparative insights with conventional T cells and mouse models.

Liyen Loh, Salomé Carcy, Harsha S Krovi, Joanne Domenico, Andrea Spengler, Yong Lin, Joshua Torres, Rishvanth K Prabakar, William Palmer, Paul J Norman and 4 more

Abstract readComparative Study
In one paragraph

Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Metabolic control of innate-like T cells.Nature reviews. Immunology · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
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  12. Article
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  14. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Liyen LohUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Salomé CarcySchool of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA; Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Harsha S KroviBrigham and Women's Hospital, Boston, MA, USA.
Joanne DomenicoUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Andrea SpenglerUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Yong LinSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Joshua TorresSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Rishvanth K PrabakarSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
William PalmerUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Paul J NormanUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Matthew StoneChildren's Hospital Colorado, Aurora, CO, USA.
Tonya BrunettiUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Hannah V MeyerSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. Electronic address: hmeyer@cshl.edu.
Laurent GapinUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address: laurent.gapin@cuanschutz.edu.

Funding

Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI David A Tuveson · 1987 to 2026
$118.9M
University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Natural Killer cells and the Immunogenetics of COVID-19R01AI158410 · NIAID · UNIVERSITY OF COLORADO DENVER · PI NORMAN, PAUL JOHN · 2021 to 2024
$2.9M
Dissecting dynamic genetic effects from thymus development to immune-mediated diseaseR01AI167862 · NIAID · COLD SPRING HARBOR LABORATORY · PI Hannah Verena Meyer · 2022 to 2026
$2.5M
TCR signal strength and iNKT cell subset developmentR01AI130198 · NIAID · UNIVERSITY OF COLORADO DENVER · PI GAPIN, LAURENT · 2018 to 2022
$1.9M
Graphical Processing Units and a Large-Memory Compute Node for Applications in Genomics, Neuroscience, and Structural BiologyS10OD028632 · OD · COLD SPRING HARBOR LABORATORY · PI SIEPEL, ADAM CHARLES · 2020 to 2020
$437k
Transcriptional Regulation of Innate T cell fateR21AI163454 · NIAID · UNIVERSITY OF COLORADO DENVER · PI GAPIN, LAURENT · 2021 to 2022
$428k
NCATS NIH HHS UL1 TR002535NCI NIH HHS P30 CA045508NCI NIH HHS P30 CA046934NIAID NIH HHS R01 AI130198NIAID NIH HHS R01 AI158410NIAID NIH HHS R01 AI167862NIAID NIH HHS R21 AI163454NIH HHS S10 OD028632
6 · The paper itself

Abstract

The "innate-like" T cell compartment, known as T

Indexed as

Immunity, InnatePhenotypeAnimalsCell DifferentiationHumansMiceMice, Inbred C57BLSingle-Cell AnalysisThymus GlandT-LymphocytesCP: Immunologygamma delta T cellsiNKTMAITT cell developmentthymus

Identifiers

PMID39264810
PMCPMC11552652

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.