ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2024
Development and Evaluation of a Real-Time Phase-Triggered Stimulation Algorithm for the CorTec Brain Interchange.
Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A RAPID PROTOTYPING ENVIRONMENT FOR CLOSED-LOOP NEUROMODULATION USING THE BRAIN INTERCHANGE SYSTEM.Proceedings of the ... Design of Medical Devices Conference. Design of Medical Devices Conference · 2026Article
- Multitarget neurostimulation of the deep brain: clinical opportunities, challenges, and emerging technologies.Journal of neural engineering · 2025Review
- A clinical grade neurostimulation implant for hierarchical control of physiological activity.bioRxiv : the preprint server for biology · 2025Article
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Authors and funding
12 authors.
Funding
Abstract
With the development and characterization of biomarkers that may reflect neural network state as well as a patient's clinical deficits, there is growing interest in more complex stimulation designs. While current implantable neuromodulation systems offer pathways to expand the design and application of adaptive stimulation paradigms, technological drawbacks of these systems limit adaptive neuromodulation exploration. In this paper, we discuss the implementation of a phase-triggered stimulation paradigm using a research platform composed of an investigational system known as the CorTec Brain Interchange (CorTec GmbH, Freiburg, Germany), and an open-source software tool known as OMNI-BIC. We then evaluate the stimulation paradigm's performance in both benchtop and in vivo human demonstrations. Our findings indicate that the Brain Interchange and OMNI-BIC platform is capable of reliable administration of phase-triggered stimulation and has the potential to help expand investigation within the adaptive neuromodulation design space.
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Registered trials
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