ArticleProceedings of the National Academy of Sciences of the United States of America2024
Host-derived CEACAM-laden vesicles engage enterotoxigenic
Abstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Research progress on multivalent genetically engineered vaccines against enterotoxigenicFrontiers in immunology · 2026Review
- Pathogenesis of adherent-invasiveGut microbes · 2025Article
- Evolution of CEACAM pathogen decoy receptors in primates.European journal of clinical investigation · 2024Article
- Current investigation of carcinoembryonic antigen cell adhesion molecule (CEACAM) biology summary of the 32nd CEA symposium: 20-23 September 2024. Würzburg, Germany.European journal of clinical investigation · 2024Article
Corrections and comments
- Update of
Authors and funding
17 authors.
Alaullah SheikhDivision of Infectious Diseases, Department of Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, MO 63110.ORCID 0000-0002-2972-6978
Debayan GanguliDivision of Infectious Diseases, Department of Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, MO 63110.ORCID 0009-0008-1899-1953
Tim J VickersDivision of Infectious Diseases, Department of Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, MO 63110.
Bernhard B SingerInstitute of Anatomy, Medical Faculty, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0002-2213-6000
Jennifer Foulke-AbelDivision of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287.ORCID 0000-0003-3882-5625
Marjahan AkhtarDivision of Infectious Diseases, Department of Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, MO 63110.
Nazia KhatoonDivision of Infectious Diseases, Department of Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, MO 63110.
Bipul SetuDivision of Infectious Diseases, Department of Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, MO 63110.ORCID 0009-0001-0208-4143
Supratim BasuDivision of Infectious Diseases, Department of Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, MO 63110.
Clayton HarroDivision of Global Disease Epidemiology and Control with the Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.
Nicole MaierCenter for Vaccine Innovation and Access, PATH, Seattle, WA 98121.
Wandy L BeattyDepartment of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110.
Subhra ChakrabortyDivision of Global Disease Epidemiology and Control with the Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.
Taufiqur R BhuiyanEnteric and Respiratory. Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka 1212, Bangladesh.ORCID 0000-0003-3755-4763
Firdausi QadriEnteric and Respiratory. Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka 1212, Bangladesh.
Mark DonowitzDivision of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287.
James M FleckensteinDivision of Infectious Diseases, Department of Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, MO 63110.ORCID 0000-0002-1148-697X
Funding
Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8MProject 3 - Human colonoids as a model for the pathobiology of EHECP01AI125181 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI ZACHOS, NICHOLAS CONSTANTINE · 2016 to 2025
$18.6MInfectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0MTranslational Research Enhancement CoreP30DK089502 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZACHOS, NICHOLAS CONSTANTINE · 2011 to 2020
$12.0MNovel Antigen Identification for an Enterotoxigenic E. coli VaccineR01AI089894 · NIAID · WASHINGTON UNIVERSITY · PI Zachary T. Berndsen, James Michael Fleckenstein · 2010 to 2026
$7.4MMolecular Pathogenesis of enterotoxigenic E. coli associated enteropathyR01AI170949 · NIAID · WASHINGTON UNIVERSITY · PI James Michael Fleckenstein · 2023 to 2026
$2.4MMolecular Pathogenesis of Enterotoxigenic Escherichia coli InfectionsI01BX001469 · VA · ST. LOUIS VA MEDICAL CENTER · PI FLECKENSTEIN, JAMES MICHAEL · 2013 to 2017
–BLRD VA I01 BX001469BLRD VA I01 BX004825HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) T32AI007172HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) P30 DK-089502NIAID NIH HHS P01 AI125181NIAID NIH HHS R01 AI089894NIAID NIH HHS R01 AI170949NIAID NIH HHS T32 AI007172NIDDK NIH HHS P30 DK052574NIDDK NIH HHS P30 DK089502U.S. Department of Veterans Affairs (VA) 5I01BX001469-05
Abstract
Enterotoxigenic
Indexed as
Bacterial ToxinsEnterotoxigenic Escherichia coliEnterotoxinsEscherichia coli InfectionsEscherichia coli ProteinsHost-Pathogen InteractionsAnimalsAntigens, CDCarcinoembryonic AntigenCell Adhesion MoleculesDiarrheaExtracellular VesiclesHumansIntestinal MucosaMiceAntigens, CDBacterial ToxinsCarcinoembryonic AntigenCD66 antigensCell Adhesion MoleculesEnterotoxinsEscherichia coli Proteinsheat-labile enterotoxin, E colicell adhesion moleculesdiarrheaenterotoxigenic Escherichia coli (ETEC)extracellular vesicleshost–pathogen interactions
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.