Evidence map›Paper›PMID 39264588›Full record

ArticleAging2024

CIB2 mediates acquired gefitinib resistance by inducing ZEB1 expression and epithelial-mesenchymal transition.

Feng-Mei Zhou, Kun-Kun Wang, Li-Hong Wang, Jian-Ge Qiu, Wei Wang, Wen-Jing Liu, Lin Wang, Bing-Hua Jiang

Abstract read
In one paragraph

Article in Aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Diverse Functions of the Calcium- and Integrin-Binding Protein Family.International journal of molecular sciences · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Feng-Mei ZhouAcademy of Medical Science, Zhengzhou University, Zhengzhou 450000, China.
Kun-Kun WangAcademy of Medical Science, Zhengzhou University, Zhengzhou 450000, China.
Li-Hong WangAcademy of Medical Science, Zhengzhou University, Zhengzhou 450000, China.
Jian-Ge QiuAcademy of Medical Science, Zhengzhou University, Zhengzhou 450000, China.
Wei WangAcademy of Medical Science, Zhengzhou University, Zhengzhou 450000, China.
Wen-Jing LiuThe Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450000, China.
Lin WangAcademy of Medical Science, Zhengzhou University, Zhengzhou 450000, China.
Bing-Hua JiangAcademy of Medical Science, Zhengzhou University, Zhengzhou 450000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

EGFR-TKIs have been used as frontline treatment in patients with advanced non-small cell lung cancer (NSCLC) suffering from the

Indexed as

Antineoplastic AgentsCarcinoma, Non-Small-Cell LungDrug Resistance, NeoplasmEpithelial-Mesenchymal TransitionGefitinibLung NeoplasmsZinc Finger E-box-Binding Homeobox 1AnimalsApoptosisCalcium-Binding ProteinsCell Line, TumorErbB ReceptorsGene Expression Regulation, NeoplasticHumansMiceProto-Oncogene Proteins c-fosAntineoplastic AgentsCalcium-Binding ProteinsErbB ReceptorsGefitinibProto-Oncogene Proteins c-fosZEB1 protein, humanZinc Finger E-box-Binding Homeobox 1CIB2EMTgefitinibnon-small cell lung cancertumor growth

Identifiers

PMID39264588
PMCPMC11424576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.