Evidence map›Paper›PMID 39264535›Full record

ArticleRheumatology and therapy2024

Fibro-adhesive Bursitis: A Novel Sonographic Finding in Adhesive Capsulitis Patients and a Proposal of Management.

Fabio Vita, Roberta Gualtierotti, Marco Miceli, Roberto Tedeschi, Flavio Origlio, Marco Cavallo, Stefano Galletti, Salvatore Massimo Stella, Enrico Guerra, Danilo Donati and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in Rheumatology and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06062654 (Ultrasound-guided Hydrodistension in Patients With Adhesive Capsulitis), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06062654 nacompletednot on this map

Ultrasound-guided Hydrodistension in Patients With Adhesive Capsulitis: a Randomized Interventional Study Aimed at Evaluating the Efficacy of Hospital-assisted Rehabilitation Treatment Compared to Home-based Rehabilitation Treatment

TypeinterventionalSponsorIstituto Ortopedico RizzoliRan2022 to 2023Enrolled46ConditionsAdhesive CapsulitisArmsHospital-assisted Rehabilitation, Home-based Rehabilitation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fabio VitaDepartment of Orthopedic and Traumatological Surgery, IRCCS Rizzoli Orthopedic Institute, University of Bologna, Bologna, Italy.
Roberta GualtierottiS.C. Medicine - Hemostasis and Thrombosis, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Pace, 9, 20122, Milan, Italy. roberta.gualtierotti@unimi.it.ORCID http://orcid.org/0000-0001-6465-7624
Marco MiceliDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Roberto TedeschiDepartment of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Flavio OriglioPhysical Therapy and Rehabilitation Unit, IRCCS Rizzoli Orthopedic Institute, University of Bologna, Bologna, Italy.
Marco CavalloShoulder and Elbow Surgery Department, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Stefano GallettiMusculoskeletal Ultrasound School, Italian Society for Ultrasound in Medicine and Biology, Bologna, Italy.
Salvatore Massimo StellaSIUMB Advanced School for Musculoskeletal Ultrasound, Department of Clinical and Experimental Medicine, University Post-Graduate Course, Santa Chiara University Hospital, Pisa, Italy.
Enrico GuerraShoulder and Elbow Surgery Department, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Danilo DonatiPhysical Therapy and Rehabilitation Unit, Policlinico di Modena, Modena, Italy.
Cesare FaldiniDepartment of Orthopedic and Traumatological Surgery, IRCCS Rizzoli Orthopedic Institute, University of Bologna, Bologna, Italy.

Funding

Ministero della Salute Ricerca Corrente
6 · The paper itself

Abstract

introductionAdhesive capsulitis, also known as "frozen shoulder," is a debilitating shoulder condition increasingly linked to fibroadhesive bursitis, particularly after COVID-19 and related vaccinations. There is no definitive gold standard for its treatment, the primary therapeutic objectives of which are the reduction of pain and the restoration of shoulder range of motion. The aim of our study was to analyze treatment outcomes based on quantitative measures of shoulder function and symptom relief.

methodConducted between January 2022 and April 2023, the research involved 45 patients initially diagnosed with adhesive capsulitis and associated fibroadhesive bursitis. After excluding nine patients for other concomitant pathologies (five for calcific tendinopathy and four for rotator cuff injury), 36 patients were randomized into two groups: one group was treated with glenohumeral hydrodistension, the other with glenohumeral hydrodistension combined with bursal injection. Assessments were conducted at baseline and then 2, 4, and 6 months after treatment, focusing on changes in pain levels, functional scores, and range of motion in all planes. Each group followed a home-based rehabilitation protocol.

resultsSignificant improvements were observed in both treatment groups, with the combined hydrodistension and bursal injection group showing notably superior outcomes. Specifically, the range of motion in flexion improved from an initial median of 80° to 155° in the combined treatment group, compared to an increase from 75.5° to 129° in the group treated with hydrodistension alone. This enhancement was statistically significant (p < 0.001). Regarding pain reduction, the combined treatment group demonstrated a dramatic decrease in visual analogue scale (VAS) scores, from a baseline median of 7 to 1 at the 6-month follow-up. In contrast, the hydrodistension-only group showed a reduction from 7 to 3, with these differences also proving statistically significant (p < 0.001).

conclusionsUltrasound-guided hydrodistension of the glenohumeral joint, if combined with bursal injection and specific exercises, effectively reduces pain, decreases disability, and improves range of motion in patients with second-stage adhesive capsulitis. This study highlights the importance of a combined approach in the management of this complex condition, especially after the histological changes that occurred after COVID-19 and related vaccinations.

trial registrationClinicalTrials.gov identifier NCT06062654.

Indexed as

Adhesive capsulitisFrozen shoulderIntra-articular injectionShoulder painUltrasonography

Identifiers

PMID39264535
PMCPMC11557800

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.