Evidence map›Paper›PMID 39264314›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

A Passive Perspiration Inspired Wearable Platform for Continuous Glucose Monitoring.

Tamoghna Saha, Muhammad Inam Khan, Samar Singh Sandhu, Lu Yin, Sara Earney, Chenyang Zhang, Omeed Djassemi, Zongnan Wang, Jintong Han, Abdulhameed Abdal and 3 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  14. Smart closed-loop drug delivery systems.Nature reviews bioengineering · 2025
    Article
  15. Review
  16. Review
  17. A Touch Enabled Hemodynamic and Metabolic Monitor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tamoghna SahaAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Muhammad Inam KhanAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Samar Singh SandhuAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Lu YinAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Sara EarneyAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Chenyang ZhangAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Omeed DjassemiAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Zongnan WangDepartment of Mechanical Engineering, University of California San Diego, La Jolla, CA, 92093, USA.
Jintong HanDepartment of Mechanical Engineering, University of California San Diego, La Jolla, CA, 92093, USA.
Abdulhameed AbdalDepartment of Mechanical Engineering, University of California San Diego, La Jolla, CA, 92093, USA.
Samarth SrivatsaDepartment of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Shichao DingAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.
Joseph WangAiiso Yufeng Li Family Department of Chemical and Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.ORCID 0000-0002-4921-9674

Funding

Center of Wearable SensorsKuwait Foundation for the Advancement of Sciences
6 · The paper itself

Abstract

The demand for glucose monitoring devices has witnessed continuous growth from the rising diabetic population. The traditional approach of blood glucose (BG) sensor strip testing generates only intermittent glucose readings. Interstitial fluid-based devices measure glucose dynamically, but their sensing approaches remain either minimally invasive or prone to skin irritation. Here, a sweat glucose monitoring system is presented, which completely operates under rest with no sweat stimulation and can generate real-time BG dynamics. Osmotically driven hydrogels, capillary action with paper microfluidics, and self-powered enzymatic biochemical sensor are used for simultaneous sweat extraction, transport, and glucose monitoring, respectively. The osmotic forces facilitate greater flux inflow and minimize sweat rate fluctuations compared to natural perspiration-based sampling. The epidermal platform is tested on fingertip and forearm under varying physiological conditions. Personalized calibration models are developed and validated to obtain real-time BG information from sweat. The estimated BG concentration showed a good correlation with measured BG concentration, with all values lying in the A+B region of consensus error grid (MARD = 10.56% (fingertip) and 13.17% (forearm)). Overall, the successful execution of such osmotically driven continuous BG monitoring system from passive sweat can be a useful addition to the next-generation continuous sweat glucose monitors.

Indexed as

Blood Glucose Self-MonitoringSweatWearable Electronic DevicesBiosensing TechniquesBlood GlucoseContinuous Glucose MonitoringEquipment DesignGlucoseHumansMonitoring, PhysiologicBlood GlucoseGlucosebiomarkercontinuous glucose monitoringelectrodessweatwearable sensor

Identifiers

PMID39264314
PMCPMC11538657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.