Evidence map›Paper›PMID 39264286›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2025

Harnessing the power of child development records to detect early neurodevelopmental disorders using Bayesian analysis.

Yuhei Hatakenaka, Koutaro Hachiya, Jakob Åsberg Johnels, Christopher Gillberg

Abstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yuhei HatakenakaFaculty of Humanities and Sociologies, University of the Ryukyus, Okinawa, Japan.ORCID 0000-0003-4100-5548
Koutaro HachiyaFaculty of Modern Life, Teikyo Heisei University, Tokyo, Japan.
Jakob Åsberg JohnelsGillberg Neuropsychiatry Centre, Sahlgrenska Academy, Gothenburg, Sweden.ORCID 0000-0002-3491-5925
Christopher GillbergGillberg Neuropsychiatry Centre, Sahlgrenska Academy, Gothenburg, Sweden.ORCID 0000-0001-8848-1934

Funding

Japan Society for the Promotion of Science 20K11101
6 · The paper itself

Abstract

aimThis study aims to analyse the developmental data from public health nurses (PHNs) to identify early indicators of neurodevelopmental disorders (NDDs) in young children using Bayesian network (BN) analysis to determine factor combinations that improve diagnosis accuracy.

methodsThe study cohort was 501 children who underwent health checkups at 18 and 36-month. Data included demographics, pregnancy, delivery, neonatal factors, maternal interviews, and physical and neurological findings. Diagnoses were made by paediatricians and child psychiatrists using standardised tools. Predictive accuracy was assessed by the receiver operating characteristic (ROC) curve analysis.

resultsWe identified several infant/toddler factors significantly associated with NDD diagnoses. Predictive factors included meconium-stained amniotic fluid, 1 min Apgar score, and early developmental milestones. ROC curve analysis showed varying predictive accuracies based on evaluation timing. The 10-month checkup was valid for screening but less reliable for excluding low-risk cases. The 18-month evaluation accurately identified children at NDD risk.

conclusionThe study demonstrates the potential of using developmental records for early NDD detection, emphasising early monitoring and intervention for at-risk children. These findings could guide future infant mental health initiatives in the community.

Indexed as

Bayes TheoremNeurodevelopmental DisordersChild DevelopmentChild, PreschoolCohort StudiesEarly DiagnosisFemaleHumansInfantMaledevelopmental recordsinfancyneonatalneurodevelopmental disorderspredictive accuracy

Identifiers

PMID39264286
PMCPMC11627451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.