Evidence map›Paper›PMID 39264263›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

A Micromanipulation-Actuated Large-Scale Screening to Identify Optimized Microphysiological Model Parameters in Skeletal Muscle Regeneration.

Xie Chen, Tao Sun, Shingo Shimoda, Huaping Wang, Qiang Huang, Toshio Fukuda, Qing Shi

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biohybrid Tendons Enhance the Power-to-Weight Ratio and Modularity of Muscle-Powered Robots.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xie ChenIntelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China.
Tao SunIntelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China.ORCID 0000-0003-1599-3466
Shingo ShimodaGraduate School of Medicine, Nagoya University, Nagoya, 466-8550, Japan.
Huaping WangIntelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China.
Qiang HuangIntelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China.
Toshio FukudaInstitute of Innovation for Future Society, Nagoya University, Nagoya, 466-8550, Japan.
Qing ShiIntelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China.

Funding

National Key R&D Program of China 2022YFB4700104National Natural Science Foundation of China 62088101National Natural Science Foundation of China 62173043National Natural Science Foundation of China U2013208
6 · The paper itself

Abstract

Hydrogel-based 3D cell cultures are extensively utilized to create biomimetic cellular microstructures. However, there is still lack of effective method for both evaluation of the complex interaction of cells with hydrogel and the functionality of the resulting micro-structures. This limitation impedes the further application of these microstructures as microphysiological models (microPMs) for the screening of potential culture condition combinations to enhance the skeletal muscle regeneration. This paper introduces a two-probe micromanipulation method for the large-scale assessment of viscoelasticity and contractile force (CF) of skeletal muscle microPMs, which are produced in high-throughput via microfluidic spinning and 96-well culture. The collected data demonstrate that viscoelasticity parameters (E

Indexed as

Muscle, SkeletalRegenerationAnimalsCell Culture TechniquesHydrogelsMiceMuscle Fibers, SkeletalTissue EngineeringHydrogelscontractile forcelarge‐scale screeningmicrophysiological modelskeletal muscle tissueviscoelasticity

Identifiers

PMID39264263
PMCPMC11600204

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.