ArticleMicrobiology spectrum2024
Augmented pathogen detection in brain abscess using metagenomic next-generation sequencing: a retrospective cohort study.
Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Metagenomic sequencing in intracranial pyogenic infections: limitations in viability and implications for antimicrobial decision-making.Annals of medicine and surgery (2012) · 2026Article
- Streptococcus anginosus group brain abscesses and subdural empyemas: exploratory compartment-specific phenotypes and discharge outcomes in a single-center retrospective cohort study.BMC infectious diseases · 2026Article
- Candida tropicalis Brain Abscess Diagnosed by Metagenomic Next-generation Sequencing.Internal medicine (Tokyo, Japan) · 2026Article
- Pediatric sinogenic intracranial abscesses: a case series and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Review
- Diagnostic value of mNGS for CNSIs in hematopoietic stem cell transplant patients.Blood science (Baltimore, Md.) · 2026Article
- Atypical Presentation of an Odontogenic Brain Abscess Due to Eggerthella lenta and Bilophila wadsworthia Coinfection.Cureus · 2026Article
- Case Report: Basal ganglia brain abscess caused byFrontiers in medicine · 2026Article
- Metagenomic Next-Generation Sequencing for Brain Abscess: Improved Pathogen Detection, Targeted Antimicrobial Therapy, and Association with Fewer Surgical Interventions.Infection and drug resistance · 2026Article
- Case Report: A rare culprit of severe pulmonary infection in children: prevotella.Frontiers in pediatrics · 2026Article
- Epidemiology of Brain Abscess: A Retrospective Cohort From a Neurosurgical Tertiary Referral Center in England.Open forum infectious diseases · 2025Article
- Novel techniques for the diagnosis of neurological infections.Current opinion in neurology · 2025Review
- The application value and challenges of metagenomic next-generation sequencing in the diagnosis of periprosthetic joint infection after arthroplasty.Frontiers in medicine · 2025Review
- Diagnostic performance and clinical utility of metagenomic next-generation sequencing in suspected central nervous system infections: a prospective comparative study.Frontiers in cellular and infection microbiology · 2025Article
- Infected pericardial effusion caused byFrontiers in cellular and infection microbiology · 2025Article
- Cost-effectiveness analysis of metagenomic next-generation sequencing versus traditional bacterial cultures for postoperative central nervous system infections in critical care settings: a prospective pilot study.Frontiers in cellular and infection microbiology · 2025Article
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Authors and funding
9 authors.
Funding
Abstract
Brain abscess is a severe infection characterized by the accumulation of pus within the brain parenchyma. Accurate identification of the causative pathogens is crucial for effective treatment and improved patient outcomes. This 10-year retrospective, single-center study aimed to compare the detection performance of conventional culture methods and metagenomic next-generation sequencing (mNGS) in brain abscess. We reviewed 612 patients diagnosed with brain abscess and identified 174 cases with confirmed etiology. The median age was 52 years, with 69.5% males. Culture tests predominately identified gram-positive bacteria, particularly
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