Evidence map›Paper›PMID 39263930›Full record

ArticleImmunotherapy2024

Case reports of immune-related cystitis and the antibody combination hypothesis.

Peng Zhang, Chunyan Yin, Ming Yang

Abstract readCase Reports
In one paragraph

Article in Immunotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Peng ZhangDepartment of Urology, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang, 315040, China.ORCID 0000-0002-8529-3687
Chunyan YinDepartment of Urology, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang, 315040, China.
Ming YangDepartment of Urology, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang, 315040, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-related cystitis is a rare condition, and its diagnostic criteria and pathogenesis are not yet fully understood. Here, we report two cases of immune-related cystitis. Both patients were previously diagnosed with lung squamous cell carcinoma and received combined treatment with immune checkpoint inhibitors and chemotherapy, leading to hemorrhagic cystitis. We reviewed the cystoscopic images and pathological features of previous cases and found that autoantibodies against hemidesmosomes may be the cause of immune-related cystitis, proposing the "antibody combination" hypothesis to explain the tissue specificity of the condition.

Indexed as

AutoantibodiesCystitisAgedCarcinoma, Squamous CellHumansImmune Checkpoint InhibitorsLung NeoplasmsMaleMiddle AgedAutoantibodiesImmune Checkpoint Inhibitorsautoantibodieshemorrhagic cystitisimmune checkpoint inhibitorsimmune-related adverse eventslung neoplasm

Identifiers

PMID39263930
PMCPMC11492643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.