Evidence map›Paper›PMID 39263919›Full record

ReviewHuman vaccines & immunotherapeutics2024

Policies for the immunization against serogroup B meningococcus for adolescents immunized during the first two years of life: A mini review.

Claudia Palmieri, Lorenza Moscara, Silvio Tafuri, Pasquale Stefanizzi

Abstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Claudia PalmieriInterdisciplinary Department of Medicine, Hygiene Unit, University of Bari Aldo Moro, Bari, Italy.
Lorenza MoscaraInterdisciplinary Department of Medicine, Hygiene Unit, University of Bari Aldo Moro, Bari, Italy.
Silvio TafuriInterdisciplinary Department of Medicine, Hygiene Unit, University of Bari Aldo Moro, Bari, Italy.
Pasquale StefanizziInterdisciplinary Department of Medicine, Hygiene Unit, University of Bari Aldo Moro, Bari, Italy.ORCID 0000-0002-3279-0196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two vaccines are available to prevent serogroup B meningococcal disease, i.e. the four-component meningococcal serogroup B vaccine (4CMenB) and the bivalent-factor-H-binding-protein meningococcal serogroup B vaccine (MenB-fHbp). Currently, 4CMenB is offered as part of routine infant immunization schedules. Available immunogenicity data showed a progressive decline in protective serum bactericidal antibodies (SBA) titers, with a re-enhancement following a booster dose during infancy. Responses did not seem to be long-lasting and vaccinated individuals might be at risk of meningococcal diseases duriṇg adolescence. Only one study evaluated the possibility to administer a single booster dose to immunocompetent adolescents who received a primary series during infancy. Despite a high proportion of enrollees achieving protective SBA levels 28 days post-booster, titers tended to decrease 1 year after. Immunocompetent adolescents who received a primary series and a booster during the first two years of life might rather benefit from re-vaccination against MenB; current evidence does not support the possibility of a booster.

Indexed as

Antibodies, BacterialImmunization ScheduleImmunization, SecondaryMeningococcal InfectionsMeningococcal VaccinesNeisseria meningitidis, Serogroup BAdolescentHealth PolicyHumansInfant4CMenB vaccineAntibodies, BacterialMeningococcal Vaccinesadolescentsboosterlong-term immunogenicityMenB vaccinesre-vaccination

Identifiers

PMID39263919
PMCPMC11404578

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.