Evidence map›Paper›PMID 39263810›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2024

Ultra-Microporous Fe-MOF with Prolonged NO Delivery in Biological Media for Therapeutic Application.

Rosana V Pinto, Chen-Chen Cao, Pengbo Lyu, Iurii Dovgaliuk, William Shepard, Eric Rivière, Cheng-Yong Su, Guillaume Maurin, Fernando Antunes, João Pires and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Metal-Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  8. Iron-MOFs for Biomedical Applications.Advanced healthcare materials · 2025
    Review
  9. Biomedical Applications of Metal-Organic Frameworks Revisited.Industrial & engineering chemistry research · 2025
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rosana V PintoCERENA, Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, 1049-001, Portugal.
Chen-Chen CaoInstitut des Matériaux Poreux de Paris, Ecole Normale Supérieure, ESPCI Paris, CNRS, PSL University, Paris, 75005, France.
Pengbo LyuICGM, Univ. Montpellier, CNRS, ENSCM, Montpellier, 34293, France.
Iurii DovgaliukInstitut des Matériaux Poreux de Paris, Ecole Normale Supérieure, ESPCI Paris, CNRS, PSL University, Paris, 75005, France.
William ShepardSynchrotron SOLEIL, L'Orme des Merisiers, Départementale 128, Saint-Aubin, 91190, France.
Eric RivièreInstitut de Chimie Moléculaire et des Matériaux d'Orsay, Université Paris-Saclay, CNRS, ICMMO, Orsay Cedex, 91405, France.
Cheng-Yong SuMOE Laboratory of Bioinorganic and Synthetic Chemistry, Lehn Institute of Functional Materials, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, China.
Guillaume MaurinICGM, Univ. Montpellier, CNRS, ENSCM, Montpellier, 34293, France.
Fernando AntunesCQE -Centro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Lisboa, 1749-016, Portugal.
João PiresCQE -Centro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Lisboa, 1749-016, Portugal.
Vânia AndréCQE - Centro de Química, Institute of Molecular Sciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, Lisboa, 1049-001, Portugal.
Carlos HenriquesCQE - Centro de Química, Institute of Molecular Sciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, Lisboa, 1049-001, Portugal.
Antoine TissotInstitut des Matériaux Poreux de Paris, Ecole Normale Supérieure, ESPCI Paris, CNRS, PSL University, Paris, 75005, France.ORCID 0000-0003-1528-7641
Moisés L PintoCERENA, Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, 1049-001, Portugal.
Christian SerreInstitut des Matériaux Poreux de Paris, Ecole Normale Supérieure, ESPCI Paris, CNRS, PSL University, Paris, 75005, France.

Funding

China Postdoctoral Science Foundation 2022M+2665Colégio da Química, Universidade de Lisboa 16/BAD/2017Fundação para a Ciência e a Tecnologia LA/P/0056/2020(IMS)Fundação para a Ciência e a Tecnologia UIDB/00100/2020&UIDB/00100/2020(CQE)Fundação para a Ciência e a Tecnologia UIDB/04028/2020&UIDP/04028/2020(CERENA)Natural Science Foundation of Hunan Province 2023JJ40621
6 · The paper itself

Abstract

Nitric oxide (NO), a key element in the regulation of essential biological mechanisms, presents huge potential as therapeutic agent in the treatment and prevention of chronic diseases. Metal-organic frameworks (MOFs) with open metal sites are promising carriers for NO therapies but delivering it over an extended period in biological media remains a great challenge due to i) a fast degradation of the material in body fluids and/or ii) a rapid replacement of NO by water molecules onto the Lewis acid sites. Here, a new ultra-narrow pores Fe bisphosphonate MOF, denoted MIP-210(Fe) or Fe(H

Indexed as

IronMetal-Organic FrameworksNitric OxideAdsorptionDrug Delivery SystemsHumansPorosityIronMetal-Organic FrameworksNitric Oxidebiological stabilityiron(III)‐MOFnitric oxide donorsopen metal sitesphosphonate

Identifiers

PMID39263810
PMCPMC11600697

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.