ReviewEClinicalMedicine2024
Utilization of colorectal cancer screening tests: a systematic review and time trend analysis of nationally representative data.
Review in EClinicalMedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pharmacist-Led Interventions for Colorectal Cancer Prevention: A Systematic Review.Current oncology (Toronto, Ont.) · 2026Pooled it
- Uptake of Colorectal Cancer Screening in Low- and Middle-Income Countries: a Systematic Review and Meta-analysis.Journal of gastrointestinal cancer · 2025Pooled it
- Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management.MedComm · 2026Review
- Leveraging Minimal Variables for Maximal Screening Yield: A Global Equity Perspective on Colorectal Cancer Risk Stratification.International journal of cancer · 2026Article
- Head-to-head comparison of the diagnostic value of fecal and serum carcinoembryonic antigen for colorectal cancer detection.International journal of cancer · 2026Article
- Variation in diagnostic performance of fecal immunochemical test (FIT) by cutoffs used in screening programs globally.EClinicalMedicine · 2026Article
- A guide to cancer screening.Nature reviews. Clinical oncology · 2026Review
- Early-detection and prevention effects of screening sigmoidoscopy: evidence from randomized trials revisited.Journal of the National Cancer Institute · 2026Article
- Inter-physician heterogeneity in colorectal cancer screening participation in France: a study based on the French National Health Data System.Archives of public health = Archives belges de sante publique · 2026Article
- Efficacy and cost-effectiveness of extending risk-stratified colorectal cancer screening: evidence from China's first province-wide program.International journal of surgery (London, England) · 2026Article
- Colonoscopy Versus Fecal Occult Blood Test Versus No Screening: A Comparative Analysis of Long-Term Effects.Deutsches Arzteblatt international · 2026Observational
- Interpretable Machine Learning Models Based on Blood Cell-Derived Inflammatory Indices for Identifying Colorectal Neoplasia: A Retrospective Study.Journal of inflammation research · 2026Article
- Strengthening colonoscopy screening in primary care: A preventive imperative before the coming surge.Journal of family medicine and primary care · 2026Article
- Application of Mendelian randomization to explore metabolic pathways in colorectal cancer.Annals of medicine and surgery (2012) · 2025Article
- Diagnostic performance of a circulating tumor DNA-based blood test compared to fecal immunochemical test in colorectal cancer screening.Cancer communications (London, England) · 2025Article
- Benchmarking progress in non-communicable diseases: a global analysis of cause-specific mortality from 2001 to 2019.Lancet (London, England) · 2025Article
- Colorectal Cancer-One Disease, Two Fires: Distinct Inflammatory Landscapes in Colon and Rectal Cancer.Diagnostics (Basel, Switzerland) · 2025Article
- Recent trends in self-reported utilization of colonoscopy and fecal occult blood test in Europe: analysis of the European Health Interview Surveys 2013-2015 and 2018-2020.European journal of epidemiology · 2025Article
- Article
- Temporal trends, disease burden and attributable risk factors of stomach and colorectal cancers among 31 countries and territories in Western Pacific region, 2000Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The substantial and increasing global burden of colorectal cancer (CRC) underscores the imperative to enhance implementation and utilization of effective CRC screening offers. Therefore, we examined the lifetime and up-to-date use of CRC screening tests across various countries, and described utilization trends over time. Methods: We conducted a systematic review on the extent and recent trends of utilization of CRC screening tests among people 45 years or older in different countries around the globe. PubMed/Medline, Web of Science, and Embase electronic databases were screened for eligible studies from inception to June 30, 2024. The study protocol was registered with international prospective register of systematic reviews (PROSPERO) (CRD42023391344). Findings: A total of 50 studies, based on nationally-representative data, were finally included - 27 from the United States (US) and 23 from other countries. The overall utilization of CRC screening has steadily increased over time in many countries, reaching 74.9% in Denmark in 2018-2020, 64% in Korea in 2020, and 72% in the US in 2021. Nevertheless, the utilization rates remain far below the national or continental targets in most countries. In contrast to European and Asian countries, where screening was predominantly fecal test-based, the approach in the US was primarily driven by colonoscopy, and the uptake of fecal tests and sigmoidoscopy gradually declined in the past two decades. Interpretation: Despite ongoing progress in CRC screening offers and utilization, there remains large potential for enhanced roll-out and utilization of effective CRC screening programs for enhanced control of CRC incidence and mortality in the years ahead. Funding: There was no funding source for this study.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.