ArticleBlood cell therapy2024
Recovery of physical function, muscle mass, and quality of life in patients undergoing allogeneic hematopoietic stem cell transplantation.
Article in Blood cell therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Preemptive hematopoietic stem cell transplantation inHaematologica · 2026Article
- Baseline Functional Performance Predicts Better Long-Term Self-Reported Physical Function After Auto-HSCT.Journal of clinical medicine · 2026Article
- Kidney Function after Hematopoietic Cell Transplantation with Orca-T, Cyclophosphamide, or Methotrexate Graft-Versus-Host Disease Prophylaxis: A Single-Center Retrospective Study.Transplantation and cellular therapy · 2026Article
- Home-based, telehealth, and hybrid exercise interventions for adults undergoing or recovering from hematopoietic stem cell transplantation: a systematic review of randomized controlled trials.Frontiers in rehabilitation sciences · 2026Review
- Factors affecting the condition and prognosis of patients with late-onset noninfectious pulmonary complications after allogeneic hematopoietic stem cell transplantation: a propensity score-matched study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Post-transplant changes in physical functioning and quality of life in patients undergoing two allogeneic hematopoietic stem cell transplants.International journal of hematology · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate the recovery of physical function, muscle mass, and quality of life (QOL) in allogeneic hematopoietic stem cell transplantation (allo-HSCT) patients 1 year after the procedure. A total of 71 patients who underwent allo-HSCT at our institution between February 2010 and June 2020, for whom a physical therapy assessment could be performed before allo-HSCT, at discharge, and 1 year after the procedure, were included. Exercise therapy during hospitalization was provided individually by a physical therapist, and exercise was self-administered after discharge. One year after allo-HSCT, handgrip strength and results of the 6-minute walk test recovered to pre-HSCT levels. However, muscle mass 1 year after allo-HSCT did not reach the pre-HSCT level. All subscales of QOL, 1 year after allo-HSCT, recovered to pre-HSCT levels, but only two of the eight subscales recovered to the national standard of 50. Multivariate analysis revealed factors associated with the recovery of physical function, muscle mass, and QOL, hemoglobin levels and albumin levels, especially among men. In contrast, factors that negatively affected recovery were age, acute graft-versus-host disease, and pre-HSCT intensity conditioning. The results suggest a potential recovery in handgrip strength, endurance, and QOL 1 year after allo-HSCT.
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Registered trials
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