Evidence map›Paper›PMID 39263615›Full record

ReviewHeart rhythm O22024

Optimizing ventricular tachycardia ablation through imaging-based assessment of arrhythmic substrate: A comprehensive review and roadmap for the future.

Janneke C Burger, Luuk H G A Hopman, Michiel J B Kemme, Wiert Hoeksema, Richard A P Takx, Rosa M Figueras I Ventura, Fernando O Campos, Gernot Plank, R Nils Planken, Cornelis P Allaart and 5 more

Abstract readReview
In one paragraph

Review in Heart rhythm O2, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Imaging phenotypes and substrates in ventricular tachycardia.Herzschrittmachertherapie & Elektrophysiologie · 2026
    Review
  2. Cardiac magnetic resonance parameters and ventricular tachycardia recurrence after catheter ablation: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  3. Review
  4. Computer-aided characterization of the arrhythmogenic substrate after myocardial infarction.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Review
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  14. From bits to bedside: entering the age of digital twins in cardiac electrophysiology.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Janneke C BurgerDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Luuk H G A HopmanDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Michiel J B KemmeDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Wiert HoeksemaDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Richard A P TakxDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Rosa M Figueras I VenturaAdas3D Medical S.L., Barcelona, Spain.
Fernando O CamposSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Gernot PlankGottfried Schatz Research Center, Division of Biophysics, Medical University of Graz, Graz, Austria.
R Nils PlankenDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Cornelis P AllaartDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Vokko P van HalmDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Pieter G PostemaDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Marco J W GötteDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Martin J BishopSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Pranav BhagirathDepartment of Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ventricular tachycardia (VT) is a life-threatening heart rhythm and has long posed a complex challenge in the field of cardiology. Recent developments in advanced imaging modalities have aimed to improve comprehension of underlying arrhythmic substrate for VT. To this extent, high-resolution cardiac magnetic resonance (CMR) and cardiac computed tomography (CCT) have emerged as tools for accurately visualizing and characterizing scar tissue, fibrosis, and other critical structural abnormalities within the heart, providing novel insights into VT triggers and substrate. However, clinical implementation of knowledge derived from these advanced imaging techniques in improving VT treatment and guiding invasive therapeutic strategies continues to pose significant challenges. A pivotal concern lies in the absence of standardized imaging protocols and analysis methodologies, resulting in a large variance in data quality and consistency. Furthermore, the clinical significance and outcomes associated with VT substrate characterization through CMR and CCT remain dynamic and subject to ongoing evolution. This highlights the need for refinement of these techniques before their reliable integration into routine patient care can be realized. The primary objectives of this study are twofold: firstly, to provide a comprehensive overview of the studies conducted over the last 15 years, summarizing the current available literature on imaging-based assessment of VT substrate. Secondly, to critically analyze and evaluate the selected studies, with the aim of providing valuable insights that can inform current clinical practice and future research.

Indexed as

Arrhythmogenic substrateCardiac computed tomographyCardiac magnetic resonance imagingImage integrationVentricular tachycardia

Identifiers

PMID39263615
PMCPMC11385403

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.