Evidence map›Paper›PMID 39263408›Full record

ReviewInternational journal of cardiology. Heart & vasculature2024

Management strategies and outcomes of thromboembolism prevention in atrial fibrillation co-existing with immune thrombocytopenia: A review of evidence.

Omar H Metwally, Alaa Rahhal, Raghad A Elsherif, Ahmed M Elshoeibi, Mohamed Elhadary, Amgad M Elshoeibi, Ahmed Badr, Basel Elsayed, Mona Al-Rasheed, Awni Alshurafa and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of cardiology. Heart & vasculature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2025
    Article
  3. Analysis of Risk Factors and the Establishment of a Predictive Model for Thrombosis in Patients with Immune Thrombocytopenia.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Omar H MetwallyCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Alaa RahhalPharmacy Department, Heart Hospital, Hamad Medical Corporation (HMC), Doha, Qatar.
Raghad A ElsherifCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Ahmed M ElshoeibiSchool of Medicine, New Giza University, Giza, Egypt.
Mohamed ElhadaryCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Amgad M ElshoeibiCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Ahmed BadrCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Basel ElsayedCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Mona Al-RasheedHematology Department, AL Adan Hospital, Kuwait City, Kuwait.
Awni AlshurafaHematology Section, Medical Oncology, National Center for Cancer Care and Research (NCCCR), Hamad Medical Corporation, Doha, Qatar.
Mohamed A YassinCollege of Medicine, QU Health, Qatar University, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aimed to assess bleeding risks and explore management options in atrial fibrillation (AF) patients with immune thrombocytopenia (ITP), aiming to formulate an optimal therapeutic approach for improved patient prognosis. Employing MeSH terms, a comprehensive search strategy identified articles on bleeding risks and management guidelines in AF combined with ITP. Original research papers were included, while animal studies, reviews, and non-English articles were excluded. From four databases, 1891 articles were initially retrieved, resulting in 10 relevant full-text articles. Eight studies investigated the effectiveness of anticoagulants in managing concurrent AF and ITP, demonstrating reduced bleeding risk and promising outcomes. Two papers explored surgical interventions, particularly left atrial appendage closure, suggesting its safety for AF management in patients with primary hemostatic disorders, including thrombocytopenia. While the pathophysiological mechanisms of AF and ITP remain unclear, anticoagulation regimens exhibited promising reductions in bleeding risks. Larger studies are warranted to enhance understanding and investigate optimal treatments for AF and ITP.

Indexed as

Atrial fibrillationBleeding risksImmune thrombocytopeniaThromboembolism prevention

Identifiers

PMID39263408
PMCPMC11387212

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.