Evidence map›Paper›PMID 39263192›Full record

ArticleJournal of nutrition and metabolism2024

Acid-Base Balance in Healthy Adults: Beneficial Effects of Bicarbonate and Sodium-Rich Mineral Water in a Randomized Controlled Trial: The BicarboWater Study.

Katharina Mansouri, Theresa Greupner, Edda van de Flierdt, Inga Schneider, Andreas Hahn

Abstract read
In one paragraph

Article in Journal of nutrition and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katharina MansouriInstitute of Food Science and Human Nutrition, Leibniz University Hanover, Hanover 30159, Germany.ORCID https://orcid.org/0009-0002-9867-2851
Theresa GreupnerInstitute of Food Science and Human Nutrition, Leibniz University Hanover, Hanover 30159, Germany.ORCID https://orcid.org/0000-0001-7510-4654
Edda van de FlierdtInstitute of Food Science and Human Nutrition, Leibniz University Hanover, Hanover 30159, Germany.ORCID https://orcid.org/0000-0003-1211-8834
Inga SchneiderInstitute of Food Science and Human Nutrition, Leibniz University Hanover, Hanover 30159, Germany.ORCID https://orcid.org/0000-0002-9296-3968
Andreas HahnInstitute of Food Science and Human Nutrition, Leibniz University Hanover, Hanover 30159, Germany.ORCID https://orcid.org/0000-0001-8459-6582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Noncommunicable diseases (NCDs) are a global health challenge. The complex etiology of NCDs involves genetic, environmental, and lifestyle factors, including dietary habits. Chronic latent metabolic acidosis has been associated with an increased risk of NCDs. Alkalizing diets and mineral water consumption have shown promise in improving acid-base balance and potentially impacting NCDs. Methods: In this randomized controlled intervention study, the effect of drinking 1,500-2,000 mL of mineral water daily on acid-base balance was evaluated. Ninety-four healthy participants were divided into two groups: one consumed mineral water with a high bicarbonate and sodium content (HBS, Results: HBS water consumption led to increased urinary pH (24-hour urine and spontaneous urine, both Conclusion: The study demonstrates that the consumption of mineral water high in bicarbonate and sodium (1,500 mL-2,000 mL/day) can positively influence urinary acid-base parameters and reduce NAE, suggesting potential benefits in maintaining acid-base balance without adverse effects on human health. These findings highlight the importance of mineral water composition in acid-base regulation. This trial is registered with DRKS00025341.

Identifiers

PMID39263192
PMCPMC11390205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.