Evidence map›Paper›PMID 39262847›Full record

ArticleToxicology reports2024

Cinnamon-mediated nano emulsion and its cryogenic activity on ROS-affected human sperm-A short study.

Parameswari Ranganathan, T B Sridharan, R Babujanarthanam, P Madhan Kumar, R Ganesamoorthy, K Thirugnanasambandham

Abstract read
In one paragraph

Article in Toxicology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Parameswari RanganathanDepartment of Biotechnology, Thiruvalluvar University, Serkkadu, Vellore 632115, India.
T B SridharanSMV 117, Gene Cloning and Technology lab, SBST, VIT, Vellore, India.
R BabujanarthanamDepartment of Biotechnology, Thiruvalluvar University, Serkkadu, Vellore 632115, India.
P Madhan KumarDepartment of Biotechnology, Thiruvalluvar University, Serkkadu, Vellore 632115, India.
R GanesamoorthyDepartment of Chemistry, Vinayaka Mission's Kirupananda Variyar Arts and Science College, Vinayaka Mission's Research Foundation (DU), Salem, Tamil Nadu 636308, India.
K ThirugnanasambandhamTamil Nadu Agricultural University, Lawley Road, Coimbatore, Tamilnadu 641003, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oil-mediated nano emulsion, a more advanced technology than other commercial extenders, will protect spermatozoa for extended periods against ROS and cryo injuries. The study is designed to elucidate the most suitable extender to preserve infertile subjects' sperm cells against ROS damage. This is a significant step forward for the andrology society, as it introduces the use of a nano emulsion extender (natural oil extract) for the first time, particularly for those who are undergoing urology-related defects. The study involved forty-four (44) infertile subjects with smoking habits and forty-two (42) fertile subjects without smoking habits, as per CASA guidelines. Semen preservatives (glycerol and egg yolk citrate), along with our naturally derived nano emulsion components (CN, EN, and EL), were prepared and used to preserve the semen sample for 24 hours. Standard semen parameters (morphology, viability, and integrity), ROS, and sperm acrosome state by staining were measured before and after cryopreservation. The results indicated that the morphology and motility of sperm features were better maintained in the CN-oil-mediated nano emulsion than in other emulsions, and ROS-induced DNA damage was reduced.

Indexed as

Acrosomal layerCinnamonCryo-nano emulsionMorphologyReactive oxygen speciesVitality

Identifiers

PMID39262847
PMCPMC11387707

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.