Evidence map›Paper›PMID 39262695›Full record

ArticleAmerican journal of translational research2024

Combination of neuromuscular electrical stimulation and ibuprofen to reduce pain in femoral head necrosis.

Boyu Liu, Ran Wei, Hongbo Zhu, Xuelu Zhao, Guang Wang

Abstract read
In one paragraph

Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Boyu LiuDepartment of Orthopedics, Affiliated Hospital of Hebei Engineering University Handan 056000, Hebei, China.
Ran WeiDepartment of Orthopedics, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine Cangzhou 056000, Hebei, China.
Hongbo ZhuDepartment of Orthopedics, Affiliated Hospital of Hebei Engineering University Handan 056000, Hebei, China.
Xuelu ZhaoDepartment of Orthopedics, Affiliated Hospital of Hebei Engineering University Handan 056000, Hebei, China.
Guang WangDepartment of Orthopedics, Cangzhou People's Hospital Cangzhou 061000, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe combinative effects of neuromuscular electrical stimulation and ibuprofen on pain in patients with femoral head necrosis were discussed and analyzed.

methodThis retrospective study analyzed data of 60 patients with femoral head necrosis hospitalized during Oct. 2020 to Oct. 2021. According to different treatment methods, the patients were divided into an observation group and a control group (30 cases in each group). The control group took oral ibuprofen sustained-release capsules, and the observation group was treated with neuromuscular electrical stimulation in addition to ibuprofen. Both groups received a 4-week treatment course. The therapeutic efficacy, Harris scale scores, Visual Analogue Scale (VAS) score, MRI hip imaging stage, SF-36 scale score, serum plasminogen activator inhibitor 1 (PAI-1), leptin and osteopontin levels before and after treatment were compared between the two groups.

resultsAfter treatment, the overall response rate in the observation group was higher than that in control group (

conclusionThe combinative treatment of neuromuscular electrical stimulation and ibuprofen has a significant effect on patients with femoral head necrosis. The treatment can remarkably reduce patients' pain, improve their hip function and quality of life, and decrease the PAI-1, leptin and osteopontin levels.

Indexed as

curative effectfemoral head necrosisibuprofenNeuromuscular electrical stimulationpain

Identifiers

PMID39262695
PMCPMC11384367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.