Evidence map›Paper›PMID 39262639›Full record

ArticleCirculation reports2024

Impact of Cardio-Ankle Vascular Index on Future Cancer in Patients With Coronary Artery Disease.

Takeshi Shimizu, Yuya Sakuma, Yuuki Muto, Fumiya Anzai, Yusuke Kimishima, Yu Sato, Akihiko Sato, Tetsuro Yokokawa, Tomofumi Misaka, Masayoshi Oikawa and 5 more

Abstract read
In one paragraph

Article in Circulation reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Takeshi ShimizuDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Yuya SakumaDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Yuuki MutoDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Fumiya AnzaiDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Yusuke KimishimaDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Yu SatoDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Akihiko SatoDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Tetsuro YokokawaDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Tomofumi MisakaDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Masayoshi OikawaDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Akiomi YoshihisaDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Takayoshi YamakiDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Kazuhiko NakazatoDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Takafumi IshidaDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.
Yasuchika TakeishiDepartment of Cardiovascular Medicine, Fukushima Medical University School of Medicine Fukushima Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular risk factors are associated with increased risk of future cancer. However, the relationship between quantitative parameters of atherosclerosis and future cancer risk is unclear. Methods and Results: A total of 1,057 consecutive patients with coronary artery disease was divided into 2 groups according to the cutoff value of the cardio-ankle vascular index (CAVI) derived by receiver operating characteristic curve analysis: low CAVI group (CAVI <8.82; n=487), and high CAVI group (CAVI ≥8.82; n=570). Patients in the high CAVI group were older and had a higher prevalence of diabetes, chronic kidney disease, anemia and history of stroke compared with patients in the low CAVI group. There were 141 new cancers during the follow-up period. The cumulative incidence of new cancer was significantly higher in the high CAVI group than in the low CAVI group (P=0.001). In a multivariate Cox proportional hazard analysis, high CAVI was found to be an independent predictor of new cancer diagnosis (hazard ratio 1.62; 95% confidence interval 1.11-2.36; P=0.012). In the analysis of individual cancer types, high CAVI was associated with lung cancer (hazard ratio 2.85; 95% confidence interval 1.01-8.07; P=0.049). Conclusions: High CAVI was associated with the risk of future cancer in patients with coronary artery disease.

Indexed as

AtherosclerosisCancerCardio-ankle vascular indexCoronary artery disease

Identifiers

PMID39262639
PMCPMC11383543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.