Evidence map›Paper›PMID 39262447›Full record

ArticleThe Lancet regional health. Europe2024

Early detection and treatment of obstructive sleep apnoea in infants with Down syndrome: a prospective, non-randomised, controlled, interventional study.

Brigitte Fauroux, Silvia Sacco, Vincent Couloigner, Alessandro Amaddeo, Aimé Ravel, Emmanuelle Prioux, Jeanne Toulas, Cécile Cieuta-Walti, Hervé Walti, Romain Luscan and 7 more

Abstract read
In one paragraph

Article in The Lancet regional health. Europe, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Brigitte FaurouxAssistance Publique-Hôpitaux de Paris (AP-HP), Pediatric Noninvasive Ventilation and Sleep Unit, Hôpital Necker Enfants Malades, Paris F-75015, France.
Silvia SaccoInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Vincent CouloignerAssistance Publique-Hôpitaux de Paris (AP-HP), Head and Neck Surgery, Hôpital Necker Enfants Malades, Paris F-75015, France.
Alessandro AmaddeoAssistance Publique-Hôpitaux de Paris (AP-HP), Pediatric Noninvasive Ventilation and Sleep Unit, Hôpital Necker Enfants Malades, Paris F-75015, France.
Aimé RavelInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Emmanuelle PriouxInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Jeanne ToulasInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Cécile Cieuta-WaltiInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Hervé WaltiInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Romain LuscanAssistance Publique-Hôpitaux de Paris (AP-HP), Head and Neck Surgery, Hôpital Necker Enfants Malades, Paris F-75015, France.
Ségolène FalqueroInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Manon ClertInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Marie-Anne CaillaudInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Livio De SanctisAssistance Publique-Hôpitaux de Paris (AP-HP), Pediatric Noninvasive Ventilation and Sleep Unit, Hôpital Necker Enfants Malades, Paris F-75015, France.
Sonia KhiraniAssistance Publique-Hôpitaux de Paris (AP-HP), Pediatric Noninvasive Ventilation and Sleep Unit, Hôpital Necker Enfants Malades, Paris F-75015, France.
Isabelle MareyInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.
Clotilde MircherInstitut Jérôme Lejeune, rue des Volontaires, Paris 75015, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infants with Down syndrome (DS) are at high risk of obstructive sleep apnoea (OSA) which is associated with neurocognitive dysfunction and behaviour problems. The aim of our study was to evaluate the effect of early OSA treatment in infants with DS on neurocognitive development and behaviour. Methods: In this prospective, interventional, non-randomised study, 40 infants with DS underwent polysomnography (PSG) every 6 months in room air between 6 and 36 months of age ( Findings: On the Griffiths III, the total score was significantly higher in the Interpretation: Early diagnosis and treatment of OSA in infants with DS may contribute to a significantly better neurocognitive outcome and behaviour at the age of 36 months. Funding: The study was funded by the Jérôme Lejeune Foundation.

Indexed as

BehaviourDown syndromeNeurocognitive functionObstructive sleep apnoeaPolysomnography

Identifiers

PMID39262447
PMCPMC11387522

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.