Evidence map›Paper›PMID 39262421›Full record

ArticleFrontiers in genetics2024

HLA-DR/DQ eplet mismatch predicts

Emmett Tsz Yeung Wong, Denise Pochinco, Anantharaman Vathsala, Wee Kun Koh, Amy Lim, Hersharan Kaur Sran, Matthew Ross D'Costa, Zi Yun Chang, Peter W Nickerson, Chris Wiebe

Abstract read
In one paragraph

Article in Frontiers in genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Imputed HLA typing as a practical approach to molecular mismatch risk stratification in kidney transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. The Progress and Challenges of Implementing HLA Molecular Matching in Clinical Practice.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emmett Tsz Yeung WongDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Denise PochincoShared Health Services Manitoba, Winnipeg, MB, Canada.
Anantharaman VathsalaDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Wee Kun KohNational University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore.
Amy LimNational University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore.
Hersharan Kaur SranDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Matthew Ross D'CostaNational University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore.
Zi Yun ChangNational University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore.
Peter W NickersonDepartment of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Chris WiebeDepartment of Medicine, University of Manitoba, Winnipeg, MB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eplet mismatch has been recognized as a more precise strategy for determining HLA compatibility by analyzing donor-recipient HLA differences at the molecular level. However, predicting post-transplant alloimmunity using single-molecule eplet mismatch categories has not been validated in Asian cohorts. We examined a cohort of Southeast Asian kidney transplant recipients (n = 234) to evaluate HLA-DR/DQ eplet mismatch as a predictor of

Indexed as

donor-specific antibodiesepletshistocompatibilityhuman leukocyte antigenkidney transplantmolecular mismatch

Identifiers

PMID39262421
PMCPMC11387181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.