Evidence map›Paper›PMID 39262416›Full record

ArticleMediators of inflammation2024

Correlation between the Systemic Immunoinflammatory Index and Platelet-Lymphocyte Ratio in Patients with Adenomyosis.

Yan Dong, YaHui Chen, YaNan Wang, Lin Wang, Yan Zhou, Mei Xue, Lin Sun

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In one paragraph

Article in Mediators of inflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yan DongDepartment of Gynecology and Obstetrics, Affiliated Hospital of Jining Medical University, Jining 272029, Shandong, China.
YaHui ChenJining Medical University, Jining 272002, Shandong, China.ORCID https://orcid.org/0009-0009-0184-9536
YaNan WangJining Medical University, Jining 272002, Shandong, China.
Lin WangJining Medical University, Jining 272002, Shandong, China.
Yan ZhouJining Medical University, Jining 272002, Shandong, China.
Mei XueJining Medical University, Jining 272002, Shandong, China.
Lin SunDepartment of Gynecology and Obstetrics, Affiliated Hospital of Jining Medical University, Jining 272029, Shandong, China.ORCID https://orcid.org/0000-0002-0376-1898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The chronic inflammatory immune response is a significant factor in the pathogenesis of benign gynecological diseases. The systemic immunoinflammatory index (SII) and the platelet-to-lymphocyte ratio (PLR) are commonly available biomarkers of inflammation. However, evidence of the relationship between SII and PLR in patients with adenomyosis is limited. This study aimed to investigate the relationship between SII and PLR in patients with adenomyosis. Methods: This cross-sectional study included 483 patients with adenomyosis who were first diagnosed at our institution between January 2019 and December 2021. Basic patient clinical information and inflammatory factors were collected for univariate analysis, smoothed curve fitting, and multivariate segmented linear regression. Results: The results of the univariate analysis showed a significant positive correlation between PLR levels and SII ( Conclusions: In conclusion, this study showed a nonlinear relationship between SII and PLR in patients with uterine adenomyosis. An increase in serum PLR levels correlates with an increase in SII before SII levels reach an inflection point.

Indexed as

AdenomyosisBlood PlateletsLymphocytesAdultBiomarkersCross-Sectional StudiesFemaleHumansInflammationLinear ModelsMiddle AgedPlatelet CountBiomarkers

Identifiers

PMID39262416
PMCPMC11390213

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