Evidence map›Paper›PMID 39262180›Full record

ArticleBJU international2024

Prediction of biochemical recurrence after radical prostatectomy from primary tumour characteristics.

Matthew J Roberts, Nathan Papa, Hans Veerman, Katelijne de Bie, Andrew Morton, Anthony Franklin, Sheliyan Raveenthiran, William J Yaxley, Maarten L Donswijk, Henk G van der Poel and 12 more

Abstract readMulticenter Study
In one paragraph

Article in BJU international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Matthew J RobertsDepartment of Urology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.ORCID 0000-0003-0552-7402
Nathan PapaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-3188-1803
Hans VeermanDepartment of Urology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.ORCID 0000-0002-2297-8179
Katelijne de BieDepartment of Urology, Amsterdam University Medical Centers, VU University, Amsterdam, The Netherlands.
Andrew MortonFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0001-9432-9509
Anthony FranklinDepartment of Urology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.ORCID 0000-0002-1954-4820
Sheliyan RaveenthiranFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-3657-9718
William J YaxleyFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-4229-1411
Maarten L DonswijkDepartment of Nuclear Medicine, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.ORCID 0000-0003-2028-9713
Henk G van der PoelDepartment of Urology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.ORCID 0000-0002-8772-1120
Hemamali SamaratungaFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0001-5796-1791
David WongI-MED Radiology, The Wesley Hospital, Brisbane, Queensland, Australia.
Nicholas BrownFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-8683-1897
Robert ParkinsonI-MED Radiology, The Wesley Hospital, Brisbane, Queensland, Australia.
Troy GianduzzoFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Boon KuaFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Geoffrey D CoughlinFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Daniela E Oprea-LagerDepartment of Radiology & Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers, VU University, Amsterdam, The Netherlands.ORCID 0000-0001-9447-2305
Louise EmmettFaculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-4895-7384
Pim J van LeeuwenDepartment of Urology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.ORCID 0000-0002-9598-5345
John W YaxleyDepartment of Urology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.ORCID 0000-0001-6566-9037
André N VisDepartment of Urology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.ORCID 0000-0003-3419-3368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo construct and externally calibrate a predictive model for early biochemical recurrence (BCR) after radical prostatectomy (RP) incorporating clinical and modern imaging characteristics of the primary tumour. PATIENTS AND

methodsPatients who underwent RP following multiparametric magnetic resonance imaging, prostate biopsy and prostate-specific membrane antigen-positron emission tomography/computed tomography (PSMA-PET/CT), from two centres in Australia and the Netherlands. The primary outcome was biochemical recurrence-free survival (BRFS), where BCR was defined as a rising PSA level of ≥0.2 ng/mL or initiation of postoperative treatment per clinician discretion. Proportional hazards models to predict time to event were developed in the Australian sample using relevant pre- and post-surgical parameters and primary tumour maximum standardised uptake value (SUV

resultsData from 846 patients were used to develop the models. Tumour SUV

conclusionTumour SUV

Indexed as

Neoplasm Recurrence, LocalProstatectomyProstate-Specific AntigenProstatic NeoplasmsAgedDisease-Free SurvivalHumansMaleMiddle AgedMultiparametric Magnetic Resonance ImagingNetherlandsPositron Emission Tomography Computed TomographyPredictive Value of TestsProstate-Specific Antigenbiochemical failureGleason scorePET/CTProstate‐specific membrane antigenPSMAradical prostatectomy

Identifiers

PMID39262180
PMCPMC11603102

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.