Evidence map›Paper›PMID 39261930›Full record

ArticleChild and adolescent psychiatry and mental health2024

Polycyclic aromatic hydrocarbon exposure effects on trajectories of maternal and adolescent mental health.

Mariah DeSerisy, Leilani Salas, Emiliya Akhundova, Dahiana Pena, Jacob W Cohen, David Pagliaccio, Julie Herbstman, Virginia Rauh, Amy E Margolis

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PubMed Full text at PMC Publisher
In one paragraph

Article in Child and adolescent psychiatry and mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mariah DeSerisyDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY, 10032, USA. md3993@cumc.columbia.edu.
Leilani SalasDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY, 10032, USA.
Emiliya AkhundovaColumbia College, Columbia University, 1130 Amsterdam Ave, New York, NY, 10027, USA.
Dahiana PenaDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY, 10032, USA.
Jacob W CohenDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY, 10032, USA.
David PagliaccioDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY, 10032, USA.
Julie HerbstmanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
Virginia RauhHeilbrunn Department of Population and Family Health, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
Amy E MargolisDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY, 10032, USA.

Funding

Translational Research Training in Child PsychiatryT32MH016434 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Cristiane S. Duarte, Kate Dimond Fitzgerald · 1985 to 2026
$10.9M
Prenatal Environmental Mixtures, Cognitive Control and Reward Processes, And Risk for Psychiatric Problems in Adolescence.R01ES032296 · NIEHS · OHIO STATE UNIVERSITY · PI MARGOLIS, AMY · 2021 to 2025
$2.6M
Training Program in Environmental Life Course EpidemiologyT32ES023772 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FACTOR-LITVAK, PAM R, PERERA, FREDERICA P · 2015 to 2019
$1.3M
Air Pollution Effects on Child Irritability and Brain ConnectivityK23ES035862 · NIEHS · OHIO STATE UNIVERSITY · PI Mariah DeSerisy · 2024 to 2026
$618k
NIEHS NIH HHS K23 ES035862NIEHS NIH HHS L40 ES035649NIEHS NIH HHS R01 ES032296NIEHS NIH HHS R01ES032296NIEHS NIH HHS T32 ES023772NIEHS NIH HHS T32-ES-023772NIMH NIH HHS T32 MH016434NIMH NIH HHS T32-MH-016434-44
6 · The paper itself

Abstract

backgroundParental psychological distress is a well-known risk factor for developmental psychopathology, with longer term parental distress associated with worse youth mental health. Neurotoxicant exposure during pregnancy is a risk factor for both poor maternal and youth mental health. The impact of one class of pollutant, polycyclic aromatic hydrocarbons (PAH), on long-term trajectories of maternal distress and youth self-reported mental health symptoms in adolescence has been understudied.

methodsPAH exposure was measured by DNA adducts in maternal blood sampled during the third trimester of pregnancy. Maternal distress, operationalized as maternal demoralization, was measured at 11 timepoints (prenatal to child age 16). Adolescent mental health symptoms were measured at age 13-15. Follow up analyses examined a subset of measures available at age 15-20 years. Structural equation modeling examined associations between PAH exposure during pregnancy and latent growth metrics of maternal distress, and between maternal distress (intercept and slope) and youth mental health symptoms in a prospective longitudinal birth cohort (N = 564 dyads).

resultsHigher prenatal PAH exposure was associated with higher concurrent maternal distress. Prenatal maternal distress was associated with adolescent's self-reported anxiety, depression, and externalizing problems. On average, maternal distress declined over time; a slower decline in mother's distress across the course of the child's life was associated with greater self-reported anxiety and externalizing problems in youth.

conclusionsOur findings are consistent with an intergenerational framework of environmental effects on mental health: PAH exposure during pregnancy affects maternal mental health, which in turn influences mental health outcomes for youth well into adolescence. Future research is necessary to elucidate the possible social and biological mechanisms (e.g., parenting, epigenetics) underlying the intergenerational transmission of the negative effects of pollution on mental health in caregiver-child dyads.

Indexed as

Child mental healthIntergenerational transmissionMaternal mental healthPolycyclic aromatic hydrocarbons

Identifiers

PMID39261930
PMCPMC11391764

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.