ArticleBMC oral health2024
Exploring the correlation between periodontal disease and serum biomarkers in haemodialysis patients.
Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Longitudinal proteomic analysis of GCF in regenerative healing of molar furcation degree II defects treated with OFD, EMD, or A-PRF + : a pilot study.Scientific reports · 2026Trial
- Oral health and salivary inflammatory markers in children and adolescents with type 1 diabetes: A cross-sectional study.Journal of endocrinological investigation · 2026Article
- Oral health status and its predictors among hemodialysis patients in Saudi Arabia: a cross-sectional study.Scientific reports · 2026Article
- Hyperuricemia is associated with periodontal ligature dysbiosis in a murine model of experimental periodontitis.Journal of oral microbiology · 2026Article
- Correlation Between Sarcopenia and Oral Health in Patients on Chronic Hemodialysis.Life (Basel, Switzerland) · 2025Article
- A Causal Association Study Between Chronic Kidney Disease and Oral Health: A Mendelian Randomization Study.Health science reports · 2025Article
- TNFAIP8L3 regulation of the TGF-β signaling pathway affects the proportion of macrophages during tumor antigen presentation and affects the prognosis of ovarian cancer.Frontiers in molecular biosciences · 2025Article
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5 authors.
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Abstract
backgroundPatients undergoing haemodialysis are more susceptible to infectious diseases, including periodontitis. This study aimed to investigate the Correlation between periodontal disease and serum markers in Yemeni haemodialysis patients.
methodsA cross-sectional study was conducted on a sample of 70 haemodialysis patients. Patient interviews, clinical examinations, and laboratory tests were performed to collect data. Serum levels of albumin, calcium, phosphorus, haemoglobin, ferritin, and creatinine were measured, with separate measurements for cystatin C The association between categorical variables was assessed using the chi-square test and Pearson's correlation coefficient, considering a significance level of p < 0.05.
resultsSignificant correlations were found between serum biomarkers and periodontal clinical parameters. Phosphorus, creatinine, albumin, ferritin, and creatinine levels correlated significantly with the Plaque Index (p < 0.001, p < 0.001, p = 0.015, p = 0.018, and p = 0.03). While the Ferritin level showed significant correlations with both the Plaque Index and Miller Classes (r = 0.281, p = 0.018 and r = 0.258, p = 0.031), respectively. The Calcium level showed a significant correlation with the Gingival Index (r = 0.266, p = 0.027). Cystatin C level was statistically correlated with mobility (r = 0.258, p = 0.031). Also, the result showed a significant correlation between Creatinine levels and Periodontitis (r = 0.26, p = 0.03).
conclusionThis study provides evidence of a strong association between periodontal disease and chronic kidney disease in Yemeni haemodialysis patients. The findings emphasize the significance of maintaining good oral health in the care of haemodialysis patients.
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